Kurskatalog forskarutbildning - VT24

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Titel Psychedelic Science – Past, Present, Future
Kursnummer 5767
Program Neurovetenskap
Språk Engelska
Antal högskolepoäng 1.5
Datum 2024-04-15 -- 2024-04-19
Kursansvarig institution Institutionen för neurobiologi, vårdvetenskap och samhälle
Särskild behörighet
Kursens syfte The purpose of the course is to provide a broad overview of psychedelic science.
Kursens lärandemål The student should after the course be able to:
- Give an account of the history of psychedelic use and research.
- Describe the current state of knowledge in the field of psychedelic science.
- Discuss methodological challenges and safety concerns related to psychedelic science.
- Present an idea for a future psychedelic research project.
Kursens innehåll The course will examine the past, present, and future of psychedelic use and research. The lectures will cover the history of psychedelic use in various cultural contexts, pharmacology and phenomenology of psychedelics, the potential therapeutic effects of psychedelic-assisted psychotherapy, and the methodological, ethical, and safety issues associated with clinical research on psychedelics. Future avenues in psychedelic research will be discussed in interactive discussions with the students.
Arbetsformer The course will run day time for one week full-time with a mix of lectures by invited internationally leading scientists, participants group assignments as well as individual studies.
Obligatoriska moment The group assignments, the oral presentations by the students and the following general discussion between all participants are compulsory. Students that are absent from these parts will have to individually submit a written presentation of the subject that needs to be presented orally to the course examinator.
Examination The examination part includes oral presentations by the students and general discussion between all participants. All students are individually assessed.
Kurslitteratur och övriga läromedel Mandatory course litterature:
Aday, J. S., Carhart-Harris, R. L., & Woolley, J. D. (2023). Emerging challenges for psychedelic therapy. JAMA psychiatry, 80(6), 533-534.

Carhart-Harris, R. L., & Friston, K. (2019). REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics. Pharmacological reviews, 71(3), 316-344.

Goodwin, G. M., Aaronson, S. T., Alvarez, O., Arden, P. C., Baker, A., Bennett, J. C., ... & Malievskaia, E. (2022). Single-dose psilocybin for a treatment-resistant episode of major depression. New England Journal of Medicine, 387(18), 1637-1648.

Johnson, M. W., Richards, W. A., & Griffiths, R. R. (2008). Human hallucinogen research: guidelines for safety. Journal of psychopharmacology, 22(6), 603-620.

Nichols, D. E. (2016). Psychedelics. Pharmacological reviews, 68(2), 264-355.

Yaden, D. B., Potash, J. B., & Griffiths, R. R. (2022). Preparing for the bursting of the psychedelic hype bubble. JAMA psychiatry, 79(10), 943-944.


Recommended course litterature:

Aday, J. S., Heifets, B. D., Pratscher, S. D., Bradley, E., Rosen, R., & Woolley, J. D. (2022). Great Expectations: Recommendations for improving the methodological rigor of psychedelic clinical trials. Psychopharmacology, 1-22.

Anderson, B. T., Danforth, A., & Grob, C. (2020). Psychedelic medicine: safety and ethical concerns. Lancet Psychiatry, 7(10).


Carhart-Harris, R. L., Roseman, L., Haijen, E., Erritzoe, D., Watts, R., Branchi, I., & Kaelen, M. (2018). Psychedelics and the essential importance of context. Journal of Psychopharmacology, 32(7), 725-731.

Dourron, H. M., Strauss, C., & Hendricks, P. S. (2022). Self-entropic broadening theory: toward a new understanding of self and behavior change informed by psychedelics and psychosis. Pharmacological Reviews, 74(4), 982-1027.

Schlag, A. K., Aday, J., Salam, I., Neill, J. C., & Nutt, D. J. (2022). Adverse effects of psychedelics: From anecdotes and misinformation to systematic science. Journal of Psychopharmacology, 36(3), 258-272.

Simonsson, O., Carlbring, P., Carhart-Harris, R., Davis, A. K., Nutt, D. J., Griffiths, R. R., ... & Goldberg, S. B. (2023). Assessing the risk of symptom worsening in psilocybin-assisted therapy for depression: a systematic review and individual participant data meta-analysis. Psychiatry Research, 115349.

Swanson, L. R. (2018). Unifying theories of psychedelic drug effects. Frontiers in pharmacology, 172.
Antal studenter 8 - 12
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
Övrig information Location: Campus Solna
Ytterligare kursledare Walter Osika
Senaste kursvärdering Kursvärderingsrapport
Kursansvarig Otto Simonsson
Institutionen för neurobiologi, vårdvetenskap och samhälle

otto.simonsson@ki.se
Kontaktpersoner Walter Osika
Institutionen för neurobiologi, vårdvetenskap och samhälle

walter.osika@ki.se