Kurskatalog forskarutbildning - VT24

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Titel Translational Medicine in the Field of Autoimmunity - an Overview
Kursnummer 2760
Program Allergi, immunologi och inflammation (Aii)
Språk Engelska
Antal högskolepoäng 3.0
Datum 2024-05-20 -- 2024-06-05
Kursansvarig institution Institutionen för medicin, Solna
Särskild behörighet Basic knowledge in immunology is required.
Kursens syfte The purpose of the course is for the students to be able to integrate their knowledge in immunology within the context of human autoimmune disease and treatment. The student should get a deeper understanding of immunological similarities and differences across various autoimmune diseases, and how clinical and translational research is conducted. The student will also get a unique patient perspective on autoimmune disease and research.
Kursens lärandemål After completing the course, the students should be able to:
-Explain immunological concepts and processes in the context of human autoimmune disease.
-Formulate research questions in relation to a clinical- and patient perspective.
-Discuss: a) parallels and distinctions between different autoimmune diseases, b) patient heterogeneity, and c) different clinical phases of a disease.
-Summarise and present research findings in the field of autoimmunity in a clear and concise manner.
Kursens innehåll The course covers immunological concepts and processes in autoimmune disorders. The students will be introduced to a number of chronic autoimmune diseases described from bedside to laboratory, including rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, skin autoimmunity, and type I diabetes. An overview of the clinical and molecular basics will be followed by a face-to-face patient-interaction, where patients describe how it is to live with an autoimmune condition, and to what extent daily life is affected. Additionally, the course will cover insights into genetic and environmental risk factors, and the role of clinical trials and patient registries – from a translational perspective – in advancing knowledge about these chronic disorders.
Arbetsformer The course is divided into two blocks of three plus three full days, comprising lectures, seminars and interactive patient-meetings/-discussions, with compulsory reading and an individual written assignment as well as a group assignment on the additional days of the course. There are also some online assignments to be completed before the first block of lectures/seminars starts. A poster session, where the students present their group assignments, will conclude the course.
Obligatoriska moment Attendance during the three plus three days is mandatory. Absence (to some extent) can be compensated by an individually written report after agreement with the course leader. The online assignments, the individual assignment (i.e. writing a short popular science article), reading of scientific articles, related group-discussions and the poster presentation, as well as giving feedback to fellow-students on the assignments, is also mandatory.
Examination The course examination includes the individual written assignment and the group assignment / poster presentation of selected topics covering cellular or molecular aspects related to autoimmune disease. The oral poster presentations will be conducted in groups of two to four students. The specific learning outcomes of the course will be subjected to critical review, in-person feedback, and individual assessment.

Kurslitteratur och övriga läromedel Compulsory reading: relevant scientific publications (the literature list will be uploaded to the course platform Canvas)
Recommended reading: relevant chapters from Janeway's Immunobiology latest edition, edited by Kenneth Murphy and Casey Weaver, Garland Publishing Inc.
Antal studenter 8 - 30
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
Övrig information The course will be given in two blocks with lectures and seminars: May 20-22 (Monday to Wednesday) and June 3-5 (Monday to Wednesday). Time between the blocks will need to be dedicated to individual and group learning assignments equivalent to four days work.
Ytterligare kursledare Caroline Grönwall, Bruno Raposo
Senaste kursvärdering Kursvärderingsrapport
Kursansvarig Karin Lundberg
Institutionen för medicin, Solna

Karin.Lundberg@ki.se
Kontaktpersoner Caroline Grönwall
Institutionen för medicin, Solna

caroline.gronwall@ki.se