Course catalogue doctoral education - VT24
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| Title | Function B - to Design Procedures and Projects Involving Research Animals |
|---|---|
| Course number | 3214 |
| Programme | 0-Inte del av forskarutbildningsprogram |
| Language | English |
| Credits | 3.0 |
| Notes |
A Laboratory Animal Science course. |
| Date | 2024-04-09 -- 2024-05-30 | Responsible KI department | Komparativ medicin |
| Specific entry requirements | Previous education in laboratory animal science to carry out scientific procedures on animals (i.e. Function A). |
| Purpose of the course | The course provides education to doctoral students and scientists who will be involved in the design of scientific procedures involving research animals as part of their research. This course also provides education in laboratory animal science to doctoral students who are not necessarily directly involved with studies using in vivo models but would like to learn how to better interpret and analyze scientific data generated from animal studies. |
| Intended learning outcomes | After completion of this course, students should be able to meet the defined learning outcomes outlined in the EU Education and Training guidelines, specifically for modules 7 (rodents), 9, 10-11, as well as encompassing learning outcomes from EU modules 1 and 2, 6.1, and 20-22. The list of suggested learning outcomes by the EU guidelines is extensive but in summary, participants will acquire the knowledge required to design and evaluate scientific procedures involving research animals. By the course's conclusion, participants should be able to:
• Demonstrate a broader and deeper level of understanding of legal requirements and responsibilities, ethics, animal welfare, and the 3Rs in relation to animal research. • Describe how to conduct scientific procedures, with or without the use of anaesthesia techniques, with a focus on rodents. • Recognize principles of sound experimental design and statistical analysis of animal studies. • Relate principles of good scientific practice in research using animals. |
| Contents of the course | This course follows the most recent EU guidelines for the education and training of persons designing scientific procedures and projects using animals, i.e. Function B, as stated in the EU Directive 2010/63 and the Swedish legislation (SJVFS 2019:9) on the protection of animals used for scientific purposes. In particular, this course will cover the Function B-specific modules established in the European Union guidelines such as modules EU 7 (Minimally invasive procedures without anesthesia for rodents and lagomorphs), EU 9 (Ethics, animal welfare, and the 3Rs - level 2), EU 10 (Design of procedures and projects - level 1), and EU 11 (Design of procedures and projects - level 2). Moreover, the course will offer a refresher on knowledge related to learning outcomes outlined in EU modules 1-2, 6.1, and 20-22.
The course contents are based on the EU Education and Training Framework and include the following areas: • Legislation, ethics, laboratory animal welfare, and the principles of the 3Rs. • Procedures pertaining to animals utilized in scientific research, with a particular emphasis on rodents. • Experimental design and the statistical analysis of animal studies. • Adherence to good scientific practices in animal research. |
| Teaching and learning activities | This course adopts a blended learning approach, combining in-person seminar lectures, webinars, e-learning, independent study, group tasks, student presentations, in-class discussions, and interactive sessions. |
| Compulsory elements | Full course attendance and active participation are mandatory. To be eligible for the final exam, students must have attended a minimum of 70% of the live sessions. Any missed parts of the course must be compensated in agreement coordination with the course leader. |
| Examination | Real-world application of acquired knowledge will be assessed through oral presentations and scenario-based discussions with feedback from teachers and the other course participants.
Theoretical knowledge will be tested with multiple-choice questions. |
| Literature and other teaching material | Handouts and e-learning material will be made available online at the learning platform Canvas. As the key reference material, the students are referred to:
1. EU legislation on the Protection of Animals Used in Science (2010). Directive 2010/63/EU. 2. Swedish legislation on the Protection of Animals Used in Science (2018). L150, SJVFS 2019:9. 3. European Commission (2014). National competent authorities for the implementation of Directive 2010/63/EU on the protection of animals used for scientific purposes. A working document on the development of a common education and training framework to fulfil the requirements under the Directive. Brussels, 19-20 February 2014. 4. Handbook of Laboratory Animal Science: Essential Principles and Practices. Hau, Jann; Schapiro, Steven Jay 3. ed.: Boca Raton: CRC Press, cop. 2011 - 723 s. ISBN:978-1-4200-8455-9 (vol.1) LIBRIS-ID:12096142 5. Lab Animal Welfare. https://flairelearning.com/course/recognition-and-prevention-of-pain-suffering-and-distress 6. Lab Animal Anaesthesia. https://flairelearning.com/course/anaesthesia-for-minor-procedures/ 7. Lab Animal Euthanasia. https://flairelearning.com/course/humane-methods-of-killing-laboratory-animals/ 8. Experimental design and statistics of animal studies. http://www.3rs-reduction.co.uk/ 9. https://learn.etplas.eu/ |
| Number of students | 8 - 14 |
| Selection of students | This course is primarily aimed at principal investigators and senior researchers, but postdoctoral fellows and doctoral students at the advanced stage of their studies are also eligible to apply. Priority will be given to individuals actively involved in projects related to animal models. |
| More information | The teaching days are scheduled in eight separate days (Apr 9, Apr 11, Apr 17, Apr 24, May 15, May 21, May 28, and May 30) between approx. 9 am and 5 pm. The course includes international, national, and local experts in laboratory animal science. This course is FELASA-accredited and follows the specific learning outcomes for Function B modules in accordance with the EC Education and Training Framework, recently endorsed by the new Swedish L150 (SJVFS 2019:9). |
| Additional course leader | |
| Latest course evaluation | Course evaluation report |
| Course responsible |
Rafael Frias Komparativ medicin 085246660 rafael.frias@ki.se |
| Contact person | - |
