Course catalogue doctoral education - VT24
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Title | Bioinformatics Analysis and Visualisation of Medical Genomics Data |
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Course number | 5633 |
Programme | Cellbiologi och genetik |
Language | English |
Credits | 3.0 |
Notes |
The course meets the requirements for a general science course. |
Date | 2023-03-06 -- 2023-03-22 | Responsible KI department | Institutionen för biovetenskaper och näringslära |
Specific entry requirements | |
Purpose of the course | To increase the understanding of the basic principles of bioinformatics and to gain practical skills in bioinformatics analysis of genomic sequencing data. |
Intended learning outcomes | After the completed course, the participants will be able to understand the principles and perform basic bioinformatics analysis of genomics sequencing data. The participants will be able to plan experimental designs and to critically evaluate the appropriateness of the different sequencing based omics methods and technologies for genome-wide gene regulation studies. |
Contents of the course | Principles of gene regulation in non-disease cases and dysregulation in diseases at individual locus level as well as on genome-wide level. Principles of sequencing based genomics technologies and corresponding bioinformatics data analysis. Concrete bioinformatics data analysis by the students of selected published projects. |
Teaching and learning activities | The course consists of preparatory work, lectures, discussion, seminars and hands-on bioinformatics analysis.
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Compulsory elements | The preparation is done in the first course week without the need to be present on-site. Week 2 consists of tasks, lectures, discussions, seminars and hands-on practicals. Both parts are compulsory. Absence has to be compensated for according to the instructions from the course leader. |
Examination | The students will be examined for all learning outcomes by their performance in (a) submitted replies to tasks given for course week 1, (b) discussions and quizzes during the course week 2, and (c) individual presentations at the last course day of their bioinformatics analysis results conducted during course week 2. |
Literature and other teaching material | Recent articles and websites. |
Number of students | 20 - 25 |
Selection of students | Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date). |
More information | The first week of the course (2023-03-06 to 2023-03-10) is in the form of individual homework assignments (distance course), as preparation for the second week of the course. Week 2 of the course (2023-03-15 to 2023-03-22) consists of tasks, lectures, discussions, and seminars in the mornings. In the afternoons, course participants will conduct data analysis in small groups under guidance of a tutor to redo key figures of selected published papers and based on the corresponding published data. The statistical language R will be used for the hands-on practical. It is strongly recommended that participants have previous experiences with R.
The course is given in collaboration with the Institute for Quantitative Biosciences at the University of Tokyo. The course faculty consists of invited speakers from the University of Tokyo and from Karolinska Institutet. The course Week 2 takes places in Tokyo, Japan. Course participants would travel to Japan and arrive in Japan latest 2023-03-14. Departure from Japan would be earliest 2023-03-23. The traveling and accommodation costs for Swedish students will not be covered by the course. Financial support for some participants (KI doctoral students/KI post docs) might be available but depends on the outcome of ongoing funding applications. Please state clearly in your course application if you are also applying for travel and accommodation support. Give detailed motivation why you would need the financial support to be able to attend the course. The relevance of your motivation will be the basis to select the funded course applicants. The recipients of this support will be selected by the course directors based on their motivation presented in their course participation application. Also, the financial support will not be shared equally over all applicants but an amount of approx. 10,000 SEK (including overhead) will be given to the selected participants. |
Additional course leader | The course co-director is Katsuhiko Shirahige from the University of Tokyo, Japan. |
Latest course evaluation | Course evaluation report |
Course responsible |
Carsten Daub Institutionen för biovetenskaper och näringslära Carsten.Daub@ki.se |
Contact person | - |
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