Course catalogue doctoral education - VT24
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Title | Lipid Metabolism and Inflammation in Cardiovascular Disease |
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Course number | 5574 |
Programme | Cardiovascular Research |
Language | English |
Credits | 1.5 |
Date | 2022-09-12 -- 2022-09-16 | Responsible KI department | Department of Medicine, Solna |
Specific entry requirements | |
Purpose of the course | This course enables the participants to obtain the up-to-date and in-depth knowledge on lipids and lipid metabolism in cardiovascular diseases, importance of lipid mediators of inflammation and its resolution, analytical methods, emphasizing both pre-clinical research and clinical aspects of cardiovascular diseases. |
Intended learning outcomes | At the end of the course, the participant should be able to:
- discuss lipid- and lipoprotein metabolism, lipid mediator biosynthesis and identify the most common analytical methods used in the field. - explain the pathophysiological importance of lipid metabolism in cardiovascular disease and be able to classify lipid mediators of inflammation and its resolution and their relevant pathways. - identify potential and currently available approaches targeting lipid mediator related inflammatory pathways for preventing or treating cardiovascular diseases - discuss challenges and developments in cardiovascular research and lipid metabolism-directed therapeutics |
Contents of the course | Topics to be covered include discussion on lipids and lipoproteins, lipid metabolism, lipid mediator biosynthesis, receptors, omega-3 fatty acids, analytical methods (e.g. GC-MS and LC-MS-MS), inflammation and its resolution in cardiovascular disease, therapeutics and state of the art in the area of both pre-clinical research and clinical aspects. Also, the participants will be encouraged and have the possibility during the course to apply these perspectives on their own projects. Critical review of contemporary key papers in the field will be performed in adjunct to lectures and seminars. |
Teaching and learning activities | The course is a full-time one week course. The teaching is partly in lecture/seminar form but also includes project work with group discussions. Time will be dedicated for an individual task focusing on different aspects covered in the lectures/seminars. The task will be presented at the end of the course followed by open discussions.
• Lectures • Seminars • Individual work • Debates of clinical issues • Presentation and discussion of assigned individual work |
Compulsory elements | The participants must attend the seminars, critical reviews of papers and the oral exam (presentation).
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Examination | Presentation of a project selected from assigned topics based on the course seminars. Critical evaluation and discussion of the other participants presentations. |
Literature and other teaching material | We will cover some of the contemporary key papers in the field. The list of reading material will be sent out to two weeks before the start of the course. |
Number of students | 8 - 25 |
Selection of students | Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date) |
More information | The course will be held Monday to Friday from 9:00 – 16:00, including breaks and individual study time. Location TBA. This course has previously been given with number 5240. |
Additional course leader | Sven-Christian Pawelzik, Magnus Bäck, Hildur Arnardottir |
Latest course evaluation | Course evaluation report |
Course responsible |
Sven-Christian Pawelzik Department of Medicine, Solna sven-christian.pawelzik@ki.se |
Contact person |
Magnus Bäck Institutionen för medicin, Solna 0851776084 Magnus.Back@ki.se Hildur Arnardottir Institutionen för medicin, Solna hildur.arnardottir@ki.se |