Course catalogue doctoral education - VT24
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Title | Clinical achievements of reproductive medicine |
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Course number | 2291 |
Programme | Development and regeneration (DevReg) |
Language | English |
Credits | 1.5 |
Date | 2022-09-05 -- 2022-09-09 | Responsible KI department | Department for Clinical Science, Intervention and Technology |
Specific entry requirements | |
Purpose of the course | The purpose of the course is to enable doctoral students to obtain a basic understanding of the biological processes involved in human reproduction. Experts in the field will provide with a fresh overview of clinical and pre-clinical research aiming at development of novel treatment possibilities but also discussing their current limitations. |
Intended learning outcomes | The learning outcomes of this course are that at the conclusion of this course students should be able to show a comprehensive view of key factors involved in reproductive biology and the processes involved in fertilization and implantation. Additionally, at the end of the course students will be able to perform a critical assessment of reported achievements on reproductive medicine and their current clinical possibilities and limitations. |
Contents of the course | Contents: Biology of the gametes, fertilization and early embryo development Normal and pathological implantation, early pregnancy loss, ectopic pregnancy, repeated miscarriage In vitro spermatogenesis and oocyte maturation Clinical investigation and therapeutic approach on female and male infertility Genetics in infertility Gonadal dysgenesia Stem cells research Assisted reproduction techniques (ART) In vitro systems and cultures Cloning. Somatic cell nuclear transfer Clinical aspects of fertility preservation Cryobiology systems for fertility preservation Pre-implantation genetic diagnosis Epigenetics in assisted reproduction Experimental reproductive tissue transplantation procedures: -ovarian and testicular tissue transplantation -transplantation of the uterus |
Teaching and learning activities | Lectures, seminars/discussions and laboratory demonstrations. |
Compulsory elements | All teaching activities, including the laboratory sessions, the lectures and the assessments, are obligatory. In case of not attendance to the activities, students should produce a literature work related with the subject of the missing activity upon agreement with the course organizer. |
Examination | Written examination and general group discussion of relevant parts of the examination. |
Literature and other teaching material | Recommended literature: Textbook of Assisted Reproductive Techniques, Fourth Edition. David K. Gardner, Ariel Weissman, Colin M. Howles, Zeev Shoham. Informa, 2012. Clinical Gynecologic Endocrinology and Infertility. Marc A. Fritz and Leon Speroff. Wolters Kluwer, 2010. Infertility; Julius Hreinsson, Lars Hamberger, Thorir Hardarson, Studentlitteratur, 2005 New micromanipulative techniques in reproductive biology. Thesis dissertation, Karolinska Institutet. José Inzunza Stockholm, 2003 (Stockholm: Karolinska University Press). Rodriguez-Wallberg KA, Oktay K. Fertility preservation during cancer treatment: clinical guidelines. Cancer management and research, 2014 Mar 4;6:105-117. |
Number of students | 8 - 16 |
Selection of students | Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date) |
More information | The course will be held in lecture rooms at Karolinska University hospital. |
Additional course leader | jose.inzunza@ki.se |
Latest course evaluation | Course evaluation report |
Course responsible |
Kenny Rodriguez-wallberg Department of Oncology-Pathology 0858580000 kenny.rodriguez-wallberg@ki.se Reproduktionsmedicin Karolinska Universitetssjukhuset Huddinge 141 86 Stockholm |
Contact person |
Cecilia Gotherstrom Institutionen för klinisk vetenskap, intervention och teknik 08-58581487 Cecilia.Gotherstrom@ki.se Klinisk Immunologi F79 Karolinska Universitetssjukhuset Huddinge 14186 Stockholm Jose Inzunza Institutionen för biovetenskaper och näringslära 08-585 850 93 Jose.Inzunza@ki.se Hälsovägen 7, Novum 141 86 Stockholm Karolina Kublickiene Institutionen för klinisk vetenskap, intervention och teknik 0735930988 Karolina.Kublickiene@ki.se Karolinska Universitetssjukhus-Huddinge campus Njurmedicin 14186 Stockholm Kenny Rodriguez-wallberg Institutionen för onkologi-patologi 0858580000 kenny.rodriguez-wallberg@ki.se Reproduktionsmedicin Karolinska Universitetssjukhuset Huddinge 141 86 Stockholm |