Course catalogue doctoral education - VT24

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Title Neural Regulation of Inflammation and Metabolism
Course number 5533
Programme 1-Ingår i flera program
Language English
Credits 1.5
Date 2022-03-14 -- 2022-03-18
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Purpose of the course The purpose of this course is to give doctoral students and post-docs insights into the neuro-immune crosstalk, particularly in the regulation of inflammation and metabolism, and how engineering, neuroscience, immunology and clinical medicine can come together to find new ways to treat disease.
Intended learning outcomes At the end of the course, the course participants will be able to: 1) Define prototypical neural circuits that regulate inflammation and metabolism, in particular in the pathogenesis of and recovery from autoimmune diseases, cardiovascular diseases and infection, 2) Identify the components of the ""inflammatory reflex"" and discuss neural regulatory mechanisms for cytokine release, 3) Contrast advantages and drawbacks with major neural based treatment approaches for inflammatory and metabolic diseases, 4) Define bioelectronic medicine and explain its potential role in clinical medicine summarize challenges in engineering and medicine for development of bioelectronic medicine technology.
Contents of the course Neural control of organ systems will be discussed in molecular, cellular and clinical perspectives. Special attention will be given to the mechanisms that detect and regulate inflammation and metabolism. The neurophysiology of nerve stimulation and other treatments that involve interfacing with the nervous system will be reviewed. Progress in neural interfacing and device development within the emerging field will be discussed.
Teaching and learning activities Lectures, a student project group and a student presentation.
Compulsory elements Lectures, project group participation, active participation in presentation and passing the examination is compulsory for ""PASS"". Limited absence from lectures can be compensated for after individual discussion with the course organizers.
Examination Project presentation and written examination.
Literature and other teaching material Presentation slides will be provided by selected lecturers at the time of the course.
Selected journal articles will also be chosen and provided, based on the newest breakthroughs within the field.
Number of students 8 - 40
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
More information This course is given jointly by the doctoral programmes Cardiovascular Research (CVR) and Allergy, immunology and inflammation (Aii). See: https://staff.ki.se/doctoral-programmes. It was previously given with the course number 2957.
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Peder Olofsson
Institutionen för medicin, Solna

Peder.Olofsson@ki.se
Contact person Laura Tarnawski
Institutionen för medicin, Solna

laura.tarnawski@ki.se