Course catalogue doctoral education - VT22

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Title Adverse outcome pathways (AOPs)-principles and applications in toxicology and health risk assessment
Course number 2986
Programme 0-Inte del av forskarutbildningsprogram
Language English
Credits 1.5
Date 2021-10-11 -- 2021-10-15
Responsible KI department Institutet för miljömedicin
Specific entry requirements
Purpose of the course The purpose of the course is to enable the acquirement of knowledge and understanding in how the concept of Adverse outcome pathways (AOPs) can provide a framework for research in toxicology and for applications for health risk assessment. An AOP is a description of a sequence of events starting with the interaction of a chemical with a biomolecule in a target cell or tissue (molecular initiating event), progressing through key events and ending in an adverse outcome.
Intended learning outcomes At the end of the course the student should be able to:
- describe the principles and components of Adverse Outcome Pathways (AOPs)
- explain how experimental studies can support the development of AOPs
- discuss how AOPs can be used as a central framework for mechanistic toxicity studies, toxicity testing and health risk assessment
Contents of the course The course will include the concept and principles of Adverse Outcome Pathways (AOPs). Development and assessment of AOPs. Examples of different AOPs. Application of the AOP concept in toxicological research and health risk assessment.
Teaching and learning activities Teaching and learning activities include lectures, exercises and group assignments.
Compulsory elements Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task.
Examination Examination is in the form of a written assignment and/or oral presentation.
Literature and other teaching material Scientific publications and reports from international organisations.
Number of students 8 - 14
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
More information The course is given also for master students in toxicology and may also include professionals from public authorities and companies.
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Annika Hanberg
Institutet för miljömedicin
08-52487526
Annika.Hanberg@ki.se
Contact person Johanna Bergman
Institutet för miljömedicin

johanna.bergman@ki.se

Nobels väg 13

17177
Stockholm