Kurskatalog forskarutbildning - VT22

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Titel Adverse outcome pathways (AOPs)-principles and applications in toxicology and health risk assessment
Kursnummer 2986
Program 0-Inte del av forskarutbildningsprogram
Språk Engelska
Antal högskolepoäng 1.5
Datum 2021-10-11 -- 2021-10-15
Kursansvarig institution Institutet för miljömedicin
Särskild behörighet
Kursens syfte The purpose of the course is to enable the acquirement of knowledge and understanding in how the concept of Adverse outcome pathways (AOPs) can provide a framework for research in toxicology and for applications for health risk assessment. An AOP is a description of a sequence of events starting with the interaction of a chemical with a biomolecule in a target cell or tissue (molecular initiating event), progressing through key events and ending in an adverse outcome.
Kursens lärandemål At the end of the course the student should be able to:
- describe the principles and components of Adverse Outcome Pathways (AOPs)
- explain how experimental studies can support the development of AOPs
- discuss how AOPs can be used as a central framework for mechanistic toxicity studies, toxicity testing and health risk assessment
Kursens innehåll The course will include the concept and principles of Adverse Outcome Pathways (AOPs). Development and assessment of AOPs. Examples of different AOPs. Application of the AOP concept in toxicological research and health risk assessment.
Arbetsformer Teaching and learning activities include lectures, exercises and group assignments.
Obligatoriska moment Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task.
Examination Examination is in the form of a written assignment and/or oral presentation.
Kurslitteratur och övriga läromedel Scientific publications and reports from international organisations.
Antal studenter 8 - 14
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
Övrig information The course is given also for master students in toxicology and may also include professionals from public authorities and companies.
Ytterligare kursledare
Senaste kursvärdering Kursvärderingsrapport
Kursansvarig Annika Hanberg
Institutet för miljömedicin
08-52487526
Annika.Hanberg@ki.se
Kontaktpersoner Johanna Bergman
Institutet för miljömedicin

johanna.bergman@ki.se

Nobels väg 13

17177
Stockholm