Syllabus database for doctoral courses
-
Startpage
Syllabus database for doctoral courses
SYLLABI FOR DOCTORAL COURSES
| Swedish title | Translationell barncancerforskning i tidsepoken av immunoterapi och omik |
|---|---|
| English title | Translational Paediatric Oncology in the Era of Immunotherapy and Omics |
| Course number | 3022 |
| Credits | 1.5 |
| Responsible KI department | Institutionen för kvinnors och barns hälsa |
| Specific entry requirements | |
| Grading | Passed /Not passed |
| Established by | The Committee for Doctoral Education |
| Established | 2021-09-20 |
| Purpose of the course | This course aims to introduce research on paediatric oncology for doctoral students and junior postdocs, with research projects in this specific area or in an adjacent area. The purpose is to enable students to:
- Obtain a comprehensive overview of the different domains within childhood cancer research and to understand the historical milestones forming the paradigms that have led to a cure of 8 out of 10 children with cancer - Get an insight into the current limitations and problems of childhood cancer treatment - To enable to get an understanding of how new methodologies in molecular biology increase our knowledge about tumorigenesis and tumor evolution. - Get an opportunity to hypothesise and suggest ideas about how to develop treatment for the remaining 2 out of 10 children with cancer. |
| Intended learning outcomes | At the end of the course the students should be able to:
- Summarize the basic epidemiological data, tumor biology and genetics, novel therapy modalities like targeted therapies and immunotherapy, including side effects, late effects and follow up within the field of paediatric oncology. - Discuss the ethical issues around childhood cancer research. - Describe and understand the principles of treatment, existing therapies, new targeted therapies and personalized medicine. - Explain and theorize the link between cancer cell biology, tumor microenvironment, immunology, genetics, and drug treatments - current knowledge and development of new drugs. - Understand and discuss the current experimental methodology applied to paediatric oncology research such as in vivo, in vitro and in silico models. - Critically evaluate research findings in paediatric oncology. - Show the acquired knowledge of mechanisms, principles, and treatment options in pediatric oncology through actively engaging in discussions with course leaders and participants. |
| Contents of the course | The students will be presented with and will discuss problems, possibilities, and research models that are specific for the research area of paediatric oncology. The course will provide a general introduction to the field and focus on distinct, but interconnected topics specific for paediatric oncology, namely ethics, epidemiology, tumor biology and genetics, existing and novel targeted drug treatments as well as immunotherapy, and side effects, late effects and follow up. The last day will be dedicated to a symposium with invited lecturers that are renowned expert in their fields.
|
| Teaching and learning activities | Lectures, seminars, group exercises with supervised discussions, either in person or online. To promote active discussion and participation, each student will prepare a poster and a short oral presentation on their current or intended research before the course and submit a short abstract on this no later than two weeks before the course start. The course will include a one-day mini research symposium. |
| Compulsory elements | All course activities are compulsory. Absence can be compensated for by other activities in agreement with the course leaders. |
| Examination | To pass the course the students must show that they have reached the learning outcomes of the course. Each student should prepare and present a scientific poster and an oral presentation on a current or intended childhood cancer research project, and answer critical questions from the course leaders and participants. Each participant in the course needs to be able not only to answer questions in a satisfactory way but also to raise relevant questions and discussion points in line with the intended learning outcomes of the course. |
| Literature and other teaching material | Recommended course literature: Current review articles (sent to the students well in advance), in addition to distributed material, including articles and book chapters. | Course responsible |
Frida Holm Institutionen för kvinnors och barns hälsa frida.holm@ki.se |
| Contact person |
Malin Wickström Institutionen för kvinnors och barns hälsa 08-51772989 0703647737 Malin.Wickstrom@ki.se Désirée Gavhed Institutionen för kvinnors och barns hälsa Desiree.Gavhed@ki.se Frida Holm Institutionen för kvinnors och barns hälsa frida.holm@ki.se Shanie Saghafian-Hedengren Institutionen för kvinnors och barns hälsa shanie.hedengren@ki.se Shahrzad Shirazi Fard Institutionen för kvinnors och barns hälsa shahrzad.shirazi.fard@ki.se |
