Syllabus database for doctoral courses

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Swedish title Funktion A - att utföra mindre procedurer på försöksdjur
English title Function A - to carry out minor procedures on laboratory animals
Course number 3160
Credits 3.0
Notes A Laboratory Animal Science course.

Responsible KI department Comparative medicine
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2018-09-24
Purpose of the course Education and training in laboratory animal science are both essential and a legal requirement for all those who need to undertake procedures on laboratory animals (Function A) for their research. The course is designed to meet the learning outcomes specified in the EU Education and Training Framework to fulfil the legal demands as set out by the Directive 2010/63/EU and by the Swedish legislation L150 (SJVFS 2017:40).
Intended learning outcomes After completion of this course, the students should be able to meet the defined learning outcomes as set out in the EU Education and Training Framework, specifically in modules 1 to 8. Such modules require either theoretical knowledge, or acquisition and demonstration of practical skills. The list of suggested learning outcomes by such guidelines is comprehensive, but in summary, participants will acquire the knowledge and skills to carry out minor procedures on research animals safely and humanely. In particular, at the end of the course participants should be able to:

1. Indicate key principles of the EU and Swedish legislation regarding the use of animals in science.
2. Understand ethical and welfare issues in relation to the use of animals in scientific procedures, including basic principles of the 3Rs (replacement, reduction, and refinement).
3. Recognize basic principles of species-specific biology and husbandry, including anatomy, physiology, reproduction, nutrition, behavior, enrichment and genetics.
4. Relate various aspects regarding animal health, care and management, including control of the environment, husbandry practices, diet, health status and disease.
5. Identify behavioral signs of discomfort, pain, suffering, and distress in animals.
6. Indicate appropriate principles and different methods of humane killing of animals.
7. Be able to approach, handle/pick up and restrain an animal according to good practice.
8. Know how to carry out minor procedures on animals such as injecting, dosing and sampling, including humane killing.
Contents of the course The course provides education and training to individuals who, during their research work with animals, will need to perform minor procedures on research animals (rodents, lagomorphs, fish, cyclostomes, aquatic amphibians, swine, or non-human primates). The course contents are based on the EU Education and Training Framework and include:
- Legislation affecting animal research.
- Ethics, animal welfare and the 3Rs.
- Species-specific basic and appropriate biology (theory and skills).
- Species-specific animal care, health and management.
- Species-specific recognition of pain, suffering and distress.
- Species-specific humane methods killing (theory and skills).
- Species-specific minimally invasive procedures without anaesthesia (theory and skills).
Teaching and learning activities The course will adopt a blended learning approach that combines web-based learning and hands-on practical training. Laboratory practical sessions are aimed at enabling the trainee to attain a level of proficiency that would eventually allow the student to work under supervision.
Compulsory elements All parts of the e-learning modules, including the examination of the theoretical parts must be successfully completed before starting the hands-on training.
Examination An exam containing short answer questions and/or multiple choice questions will be used to assess theoretical knowledge. Practical skills are assessed during the laboratory session using direct observation of practical skills.
Literature and other teaching material 1. EU legislation on the Protection of Animals Used in Science (2010). Directive 2010/63/EU.
2. Swedish legislation on the Protection of Animals Used in Science (2018). L150, SJVFS 2017:40.
3. European Commission (2014). National competent authorities for the implementation of Directive 2010/63/EU on the protection of animals used for scientific purposes. A working document on the development of a common education and training framework to fulfil the requirements under the Directive. Brussels, 19-20 February 2014.
4. Handbook of Laboratory Animal Science: Essential Principles and Practices. Hau, Jann; Schapiro, Steven Jay 3. ed.: Boca Raton: CRC Press, cop. 2011 - 723 s. ISBN:978-1-4200-8455-9 (vol.1) LIBRIS-ID:12096142
5. Lab Animal Welfare.
6. Lab Animal Euthanasia.
Course responsible Rafael Frias
Comparative medicine

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