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Swedish title Vårdrelaterade infektioner och antibiotikaresistens i högendemiskt område
English title Hospital acquired infections and antibiotic resistance in high endemic setting
Course number 2929
Credits 3.0
Responsible KI department Department of Global Public Health
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2017-03-21
Purpose of the course To enable doctoral students in the field of global health and/or infectious diseases and infection control or with a genuine interest in these areas to acquire good knowledge about: antibiotic resistance development in community and hospital and the impact on patient care, transmission of hospital acquired infections of (HAI), the burden of HAI including excess morbidity, mortality and costs as well as strategies to prevent selection of antibiotic resistance and HAI through surveillance, screening, infection control and antibiotic stewardship as well as HAI case management.
Intended learning outcomes - To understand the development of antibiotic resistance development and the impact of antibiotic selective pressure on bacteria
- To understand the factors influencing antibiotic resistance and including health seeking pattern, health system, antibiotic use in community and hospital, economic incentives and perception of health and treatment in the population.
- To understand the risk factors and transmission of HAI in high endemic settings.
- To understand surveillance of HAI in health care facilities, the diagnostic criteria, diagnostics, treatment and follow up.
- To understand the burden of HAI including excess morbidity, mortality and costs due to HAI
- To understand measures to prevent HAI including infection control measures and antibiotic stewardship.
Contents of the course Risk factors for antibiotic resistance development including health seeking pattern, health system, antibiotic use in community and hospital, economic incentives and perception of health and treatment in the population as well as agricultural use of antibiotics and how antibiotics and antibiotic resistance is spread in the environment.
Transmission of Hospital Acquired G- Infections, especially carabapenem resistant strains of Klebsiella Pneumonia, Acinetobacter Baumannii, Pseudomonas Aeruginosa and how it effects critical care as well as measures to prevent spread as Surveillance, Screening, Infection Control and Antibiotic Stewardship .
Teaching and learning activities - There will be one introduction lecture at Karolinska Institutet prior to departure.
- Lectures (might be spread out during the course) in total two days focusing on the learning outcomes.
- Two days in a provincial setting to understand the living conditions and selective pressure for resistance development including animal and humans use of antibiotics and how it is spread in the environment.
- Bed side teaching at tertiary referral hospitals to get an understanding regarding the prevalence and spread of G- infections, as well as measures to prevent spread as Surveillance, Screening, Infection Control and Antibiotic Stewardship.
- Group work, e.g family visit and patient cases that are presented and discussed.
Compulsory elements All the course activities are mandatory. Absence might be compensated for through assignments in agreement with the course leader.
Examination Formative assessment during group work presentations and discussion.
Summative written examination at Karolinska Institutet
Literature and other teaching material Recommended literature: Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE), Center for Disease Control (CDC), 2012.
Relevant research articles about Tropical Medicine and Infections will be distributed latest at the time of the introductory lecture.
Course responsible Mattias Larsson
Department of Global Public Health
0852483382

Mattias.Larsson@ki.se
Contact person