Kurskatalog forskarutbildning - VT22

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Titel Basic Immunology
Kursnummer 3187
Program Allergi, immunologi och inflammation (Aii)
Språk Engelska
Antal högskolepoäng 3.0
Datum 2021-09-06 -- 2021-09-24
Kursansvarig institution Institutionen för klinisk neurovetenskap
Särskild behörighet Knowledge in basic cell biology
Kursens syfte To give doctoral students the possibility to acquire a solid knowledge and understanding of fundamental principles in immunology. All other courses in the doctoral education program Aii (Allergy, immunology and inflammation) assume that students have taken the Basic Immunology course, or otherwise have attained the same level of previous knowledge and understanding.
Kursens lärandemål To be able to:
- Explain the basic principles of innate and adaptive immunity and how different components of the immune system cooperate.
- Describe and compare principles of immune-related diseases in a clinical perspective.
- Apply knowledge gained on the function of the immune system to propose an experimental project in immunology in the form of a written assignment, that will be discussed in pairs.
- Review a chosen immune cell type/process/disease, which will be presented as a group project.
Kursens innehåll The course is separated into two parts. In part 1 we discuss basic immunological mechanisms within the innate and adaptive immune response. In part 2 we apply the knowledge in clinical settings such as defence against infection, autoimmune and allergic diseases or transplantation.
Part 1: An overview of the immune system, T cells, B cells, Antigen presenting cells, Innate lymphoid cells, Innate vs adaptive immune responses.
Part 2: Immune defence against bacterial and viral infections, Primary immunodeficiencies, Autoimmune disease, Allergy, Vaccination, Clinical Immunology, Transplantation, Tumour Immunology. Questions and discussions. Presentation of projects.
Arbetsformer The course consists of lectures and seminars arranged during mornings five days per week. In the afternoon, students are assigned for reading to prepare for the next day’s topics as well as project work, further reading, meeting with mentors and a written assignment.
Course literature will be available on the course platform in advance of the course start and will be the basis for active discussion during the lectures. We will run exercises and immunological quizzes connected to the different parts of the course, so that the student will be able to digest the relatively big material.
On the last day of the course the project work will be presented orally.
Obligatoriska moment All activities included in the course are compulsory. Absence needs to be compensated for in agreement with the course director.
Examination Each student will be examined on the project work and the written assignment, as well as its contributions during the discussions. The project work will be evaluated by the group project mentor and by the course organizers during the oral presentations of the work. The individual written assignment is evaluated by the course organizers and will be discussed in pairs.
Kurslitteratur och övriga läromedel Mandatory literature:
Abul K. Abbas, Andrew H. Lichtman and Shiv Pillai: Basic Immunology: Functions and Disorders of the Immune System. Latest edition. (Elsevier – Health Sciences Edition).
Lecture handouts uploaded to the course website. Scientific review articles proposed by group project mentors.
Antal studenter 20 - 35
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
Övrig information The course is divided into two sessions with 5 mornings of lectures each, September 6th to 10th (Monday to Friday) and September 20th to 24th (Monday to Friday). The afternoons will be dedicated to individual and group learning activities. Group presentation will be given on Friday September 24th. Teachers include specialists in different fields of immunology including both basic and clinical researchers. This course has previously been given with number 5229. The course will take place at CMM (Karolinska Institutet, Solna) and/or through Zoom, following the university's recommendations.
Ytterligare kursledare andre.ortlieb@ki.se
Senaste kursvärdering Kursvärderingsrapport
Kursansvarig Nicolas Ruffin
Institutionen för klinisk neurovetenskap

nicolas.ruffin@ki.se
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