Course catalogue doctoral education - VT21

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Title Neural Control of Inflammation: An introduction to Bioelectronic Medicine
Course number 2957
Programme 1-Ingår i flera program
Language English
Credits 1.5
Date 2021-04-19 -- 2021-04-23
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Purpose of the course The purpose of this course is to give doctoral students insights into the neural control of homeostasis, particularly the regulation of inflammation, and how engineering, neuroscience, immunology and clinical medicine can come together to find new ways to treat disease.
Intended learning outcomes After the course, the doctoral student will be able to
define prototypical neural circuits that regulate homeostasis
explain the role of inflammation in the pathogenesis of and recovery from autoimmune diseases, cardiovascular diseases and infection
identify the components of the ""inflammatory reflex""
discuss regulatory mechanisms for cytokine release
classify different interfaces with the nervous system and the immune system
contrast advantages and drawbacks with major treatment approaches for inflammatory diseases
describe molecular sensors for danger in the immune system and the nervous system
define bioelectronic medicine and explain its potential role in clinical medicine
summarize challenges in engineering and medicine for development of bioelectronic medicine technology
Contents of the course Neural control of organ systems will be discussed in molecular, cellular and clinical perspectives. Special attention will be given to the mechanisms that detect and regulate inflammation. The neurophysiology of vagus nerve stimulation and other treatments that involve interfacing with the nervous system will be reviewed. Progress in neural interfacing and device development within the emerging field of Bioelectronic Medicine will be discussed.
Teaching and learning activities Lectures, a student project group and a student presentation.
Compulsory elements Lectures, project group participation, active participation in presentation and passing the examination is compulsory for ""PASS"". Limited absence from lectures can be compensated for after individual discussion with the course organizers.
Examination Project presentation and written examination.
Literature and other teaching material Relevant articles and other written material will be made available after admission.
Number of students 8 - 40
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
More information Full time, Monday to Friday. Karolinska Solna. This course is given jointly by the doctoral programmes Allergy, immunology and inflamation (Aii) and Cardiovascular research (CVR). See:
Additional course leader Laura Tarnawski (
Latest course evaluation Course evaluation report
Course responsible Peder Olofsson
Institutionen för medicin, Solna
Contact person Laura Tarnawski
Institutionen för medicin, Solna