Course catalogue doctoral education - VT21

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Title Basic Inflammation
Course number 2705
Programme Allergi, immunologi och inflammation (Aii)
Language English
Credits 3.0
Date 2021-03-22 -- 2021-04-16
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements Documented knowledge about basic concepts of innate and adaptive immunity (e.g. immunology course during undergraduate education)
Purpose of the course This course will give a general and broad overview knowledge in the field of inflammation. Ability to think critically will be encouraged during discussions and group work.
Intended learning outcomes After the course, the participant will be able to: understand cellular and molecular events those underlie the initiation, progression and resolution of inflammation; to describe the principal cell types involved in inflammatory responses and their interactions, the regulation of inflammation by inflammatory mediators, and the mechanisms of resolution and tissue repair; to understand the interplay between acute and chronic inflammation in the context of chronic inflammatory diseases and describe anti-inflammatory treatment strategies.
Contents of the course The course provides the current concept of inflammation and consists of two parts. Part 1 will cover the basic mechanisms and mediators of inflammation (host defence peptides, coagulation, complement, alarmins, lipid mediators, the acute phase proteins, inflammatory cells), non-resolving inflammation, resolution of inflammation. Part 2 will discuss the common and specific features of inflammatory diseases (sepsis, chronic inflammatory diseases), animal models of inflammation, role of genetic and environmental factors, anti-inflammatory treatment. At the end of the course the students will present projects and write web-based exam.
Teaching and learning activities Lectures, journal clubs, small-group work with a project, discussions and the project presentation, studying the course literature. The course is full-time for six days separated into two parts and also includes the non-scheduled time (32h) between the parts for the project work including meetings with mentors and the course literature studies.
Compulsory elements The participants must attend the seminars, critical reviews of papers and the oral exam (presentation). Absence has to be compensated for by assignments in agreement with the course leader within 4 weeks from the absence.
Examination Presentation of the project selected from assigned topics based on the course seminars. Critical evaluation and discussion of the other participants' presentations.
Literature and other teaching material Chapters of Book Fundamentals of Inflammation (Cambridge University Press) and published review state-of-the-art articles within the relevant research area.
Number of students 10 - 30
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date).
More information 22-24 March: Lectures. 25 March - 13 April: Group work, no scheduled time. 14-16 April: Lectures and presentations.
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Cecilia Aulin
Institutionen för medicin, Solna

cecilia.aulin@ki.se
Contact person Cecilia Aulin
Institutionen för medicin, Solna

cecilia.aulin@ki.se