Course catalogue doctoral education - VT21

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  • Ansökan kan ske mellan 2020-10-15 och 2020-11-16
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Title Lipids and Lipid-Metabolic Driven Inflammation in Cardiovascular Disease – Basic Science and Clinical Aspects
Course number 5240
Programme Kardiovaskulär forskning
Language English
Credits 1.5
Date 2020-09-14 -- 2020-09-18
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Purpose of the course This course provides the participants with the up-to-date knowledge on lipids and lipid metabolism in cardiovascular diseases, importance of lipid mediators of inflammation- resolution, analytical methods and metabolomics, emphasizing both pre-clinical research work and clinical aspects of cardiovascular diseases.
Intended learning outcomes At the end of the course, the participant should show:

- a general understanding of lipid and lipoprotein metabolism, lipid mediators of inflammation-resolution in cardiovascular diseases, the research and analytical methods used in the field and clinical aspects.

- a good understanding of the pathophysiological importance of lipid metabolism and lipid mediators in cardiovascular diseases.

- a clear view of potential and currently available approaches targeting lipid metabolism for preventing or treating cardiovascular diseases

- an ability to apply established knowledge to discuss challenges and developments in cardiovascular research and therapeutics targeting lipid metabolism
Contents of the course The course module will provide course participants with in-depth knowledge of specific areas of lipid metabolism, metabolomics and inflammation-resolution in cardiovascular diseases, as well as an overview of the state of the art in the area of both pre-clinical research and clinical aspects. Topics to be covered include discussion on lipids and lipoproteins, lipid metabolism, lipid mediator biosynthesis, receptors, omega-3 fatty acids, analytical methods (e.g. GC-MS and LC-MS-MS), inflammation and its resolution, therapeutics and clinical studies. Also, the participants will be encouraged and have the possibility during the course to apply these perspectives on their own projects. Critical review of contemporary key papers in the field will be performed in adjunct to lectures and seminars.
Teaching and learning activities The course is a full-time one week course. The teaching is partly in lecture/seminar form but also includes project work with group discussions. Time will be dedicated for an individual task focusing on different aspects covered in the lectures/seminars. The task will be presented at the end of the course followed by open discussions.

• Lectures
• Seminars
• Individual work
• Debates of clinical issues
• Presentation and discussion of assigned individual work
Compulsory elements The participants must attend the seminars, critical reviews of papers and the oral exam (presentation). Absence has to be compensated for by a written assignment in agreement with the course leader within 4 weeks.
Examination Presentation of a project selected from assigned topics based on the course seminars. Critical evaluation and discussion of the other participants presentations.
Literature and other teaching material Selected journal articles with significant contributions to the fields covered in the course.
Number of students 8 - 20
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
More information The course will be held Monday to Friday from 9:00 – 16:00 at DNA lecture room NEO building, Flemingsberg Campus.
Additional course leader Magnus Bäck, Sven-Christian Pawelzik
Latest course evaluation Course evaluation report
Course responsible Hildur Arnardottir
Institutionen för medicin, Solna

hildur.arnardottir@ki.se
Contact person Magnus Bäck
Institutionen för medicin, Solna
0851776084
Magnus.Back@ki.se