Course catalogue doctoral education - HT20

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Title Cardiovascular epidemiology
Course number 3132
Programme 1-Ingår i flera program
Language English
Credits 1.5
Date 2019-11-18 -- 2019-11-22
Responsible KI department Institutet för miljömedicin
Specific entry requirements
Purpose of the course This course focuses on the application of epidemiological study designs to understand and evaluate risk factors for common cardiovascular diseases.
Intended learning outcomes Students having successfully completed this course should be able to:
- Explain the theoretical difference between risk factors and risk indicators for cardiovascular diseases;
- Explain potential mechanisms underlying the effect of risk factors in the atherosclerotic process;
- Discuss the differences among the different common epidemiological study designs used within the cardiovascular epidemiology research area;
- Interpret study results critically by considering the different sources of bias.
Contents of the course The course introduces basic epidemiological concepts and common epidemiological study designs such as cohort studies, case-control studies, clinical trials and genetic association studies. During the course choice of epidemiological study design as well as potential sources of bias will be discussed using practical examples.

During the course special attention will be given to discuss:
-established and emerging cardiovascular risk factors;
-potential mechanisms underlying atherosclerosis and its main clinical outcomes of interest in the field of cardiovascular epidemiology;
-theories and concepts related to common epidemiological study designs: case control, cohort and clinical trials;
-the emerging role of biomarkers in cardiovascular research;
-the role of genetic- and environmental interactions.

No specific background knowledge is formally required to be eligible for the course.
However, before the course begins students are recommended to do a self-assessment regarding some important basic concepts (within epidemiology and cardiology). This test will be distributed to course participants about two weeks before the beginning of the course. The students may use some of the literature indicated in the course literature to fill in gaps of knowledge if needed. On the first day of the course we will go through the test and briefly discuss together the questions and the answers.
Teaching and learning activities Apart from lectures, the course will include group work and seminars in order to facilitate learning. Group tasks will include critical discussions of research articles in order for students to practice their skills in the evaluation of study designs and results. Individually, but also in pairs, students will work on exercise questions.
Compulsory elements Individual written examination, group work on day 2 and on day 4 of the course.
Examination Learning outcomes will be assessed using 1) a short individual written examination, and 2) oral presentations of group work.
Literature and other teaching material Suggested course literature

Rothman K J: Epidemiology: An introduction. Oxford University Press 2002.
Chapter 2: What is causation? Page 8
Chapter 3: Measuring Disease Occurrence and Causal Effects. Page 24
Chapter 4: Types of Epidemiological Studies. Page 57
Chapter 5: Biases in Study Design. Page 94

Libby P, Bonow R, Mann D, Zipes D. Braunwald´s Heart Disease. 8th Edition 2010.
Chapter 1: Global Burden of Cardiovascular Disease. Page 1
Chapter 38: The Vascular Biology of Atherosclerosis. Page 985

Compendium on Basic principles in Epidemiology

Compendium on Basic principles of Cardiovascular Biology
Number of students 8 - 25
Selection of students Eligible doctoral students will be selected based on 1) the relevance of the syllabus for the applicant's doctoral project (according to written motivation), and 2) date for registration as doctoral student (priority given to earlier registration date). To be considered, submit a completed application form. Give all information requested, including a description of current research and motivation for attending, and an account of previous courses taken.
More information The course is arranged in collaboration between the Epidemiology and Cardiovascular research Programmes, please see
This course has previously been given with course number 2154.
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Karin Leander
Institutet för miljömedicin

Box 210 (Nobels väg 13), KI

171 77
Contact person Johanna Bergman
Institutet för miljömedicin

Nobels väg 13