Course catalogue doctoral education - HT21

  • Ansökan kan ske mellan 2021-04-15 och 2021-05-17
Application closed
Title Clinical Applications in Musculoskeletal Regenerative Medicine
Course number 2818
Programme X- Används inte längre - Regenerativ medicin
Language English
Credits 1.5
Date 2015-06-01 -- 2015-06-05
Responsible KI department Institutionen för klinisk vetenskap, intervention och teknik
Specific entry requirements none
Intended learning outcomes At the end of the course, the doctoral student will be able to describe: 1) basics of stem cell biology, stem cell differentiation, and the stem cell niche, 2) a number of novel technologies and approaches in stem cell research and regenerative medicine, 3) strategies for safe and effective translation of basic stem cell biology into the clinic.

The student can demonstrate an interdisciplinary understanding of central concepts in stem cell science and critically evaluate different methods and techniques used. The student will be able to extract and integrate information from state-of-the-art lectures in combination with overview articles and literature searches on the internet within the research field.
Contents of the course The course covers key concepts in translational research on stem cells and the stem cell niche from the laboratory to the patient in the clinic. This includes a general overview of stem cell biology and history, sources, homing and circulation and interaction with the immune system, and clinical applications. Invited speakers will give advanced summaries of the latest research in the stem cell and regenerative medicine field.
Teaching and learning activities The pedagogic framing of this course is based on lectures with corresponding research topics. The student will be welcomed to take an active part, contribute and value discussions on relevant topics in the stem cell field. Networking with students and speakers is highly encouraged in this course.
Compulsory elements The lectures and examination are mandatory. Compensation according to the instructions of the course director.
Examination Individual written project report will be performed and handed in at the end of the course. Formative assessment of each student in connection with discussions with lectures and peers.
Literature and other teaching material The course literature will consist of recent original and review papers on selected topics within the field of stem cells and the stem cell niche as well as the latest articles from the speakers¿ lecturers. Handouts from the lecturers will also be included.

Examples of review articles:
- Viviane Tabar & Lorenz Studer. Pluripotent stem cells in regenerative medicine: challenges and recent progress. Nature Reviews Genetics. 2014; 15, 82-92
- Avital Mendelson & Paul S Frenette. Hematopoietic stem cell niche maintenance during homeostasis and regeneration. Nature Medicine. 2014; 20, 833-846
- Stefanie Dimmeler, Sheng Ding, Thomas A Rando & Alan Trounson. Translational strategies and challenges in regenerative medicine. Nature Medicine. 2014; 20, 814-821
- Ilic D. Stem cell based therapy-where are we going? Lancet. 2012; 379(9819):877-8.
- Trounson A. Clinical trials for stem cell therapies. BMC Med. 2011; 9:52.
- Chien, K.R. Regenerative medicine and human models of human disease. Nature. 2008; 453(7193):302-5.
- Ankrum J. Mesenchymal stem cell therapy: Two steps forward, one step back. Trends Mol Med. 2010; (5):203-9.
Keating A. Mesenchymal stromal cells: new directions. Cell Stem Cell. 2012; 10(6):709-16.
- Le Blanc K. Multipotent mesenchymal stromal cells and the innate immune system. Nat Rev Immunol. 2012; 12(5):383-96.

Examples of webpages:
Number of students 10 - 25
Selection of students The selection process will be based on a comprehensive assessment of the students: 1. Motivation for the course 2. Topic of their PhD project 3. Years since PhD registration
More information The KI-CUHK (the Chinese University of Hong Kong) International Network Symposium on Regenerative Medicine will be a part of the course and will be held on June 1-2, 2015. International and national key experts will lecture at the course.
Additional course leader
Latest course evaluation Not available
Course responsible Ju Luan
Institutionen för klinisk vetenskap, intervention och teknik
Contact person Cecilia Gotherstrom
Institutionen för klinisk vetenskap, intervention och teknik

Klinisk Immunologi F79
Karolinska Universitetssjukhuset Huddinge