Syllabus database for doctoral courses
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Syllabus database for doctoral courses
SYLLABI FOR DOCTORAL COURSES
| Swedish title | Celltransplantation |
|---|---|
| English title | Cell transplantation |
| Course number | 2557 |
| Credits | 2.0 |
| Responsible KI department | Institutionen för klinisk vetenskap, intervention och teknik |
| Specific entry requirements | None |
| Grading | Passed /Not passed |
| Established by | The Board of Doctoral Education |
| Established | 2011-09-01 |
| Purpose of the course | |
| Intended learning outcomes | After the course, the student will be able to describe the basics of stem cell biology and the immunological mechanisms behind engraftment and rejection, and how tolerance develops after transplantation. The student will also be able to describe how central animal models used in transplantation research function. The student will be able to extract and integrate information from state-of-the-art lectures in combination with overview articles and literature searches on the internet within the research field. |
| Contents of the course | The course covers key concepts in translational cell transplantation research from the laboratory to the patient in the clinic. This includes a general overview of stem cell biology, transplantation immunology and the most common animal models used in transplantation research. Furthermore, an advanced summary of the latest events in the transplantation field will be given by experts. Ethical dilemmas in the transplantation area will be presented and discussed. The student take an active part, contribute and value discussions on ethical predicaments in the transplantation area. |
| Teaching and learning activities | The pedagogic framing of this course is based on lectures with corresponding review papers. The course includes workshops with illustrative predicaments where the students are required to take an active part in the discussions. Group discussions in pairs will be conducted where the students discuss and integrate information from the lectures and review papers, which should be supplemented with information from other sources, like the internet. The students prepare and present their work in a written report. |
| Compulsory elements | Absence from obligatory parts (the discussion on ethical dilemmas) of the course is compensated according to instructions from the course director. |
| Examination | Written project report that will be performed and handed in at the end of the course. The individual performance of each student will be evaluated separately. |
| Literature and other teaching material | The course literature will be 3-5 review papers on selected topics within the field of cell transplantation as well as the latest articles from the expert lecturers. Handouts from the lecturers will also be included. Examples of webpages: http://stemcells.nih.gov/ http://www.explorestemcells.co.uk/ Examples of review articles: Chien, K.R. Regenerative medicine and human models of human disease. Nature. 2008 May 15;453(7193):302-5. Gordon, M.Y. Stem cells for regenerative medicine -Biological attributes and clinical application. Exp Hematol. 2008 Jun;36(6):726-32. Mimeault, M., Hauke, R. & Batra, S.K. Stem cells: a revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin Pharmacol Ther. 2007 Sep;82(3):252-64. |
Course responsible |
Cecilia Gotherstrom Institutionen för klinisk vetenskap, intervention och teknik 08-58581487 070-4712300 Cecilia.Gotherstrom@ki.se Klinisk Immunologi F79 Karolinska Universitetssjukhuset Huddinge 14186 Stockholm |
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