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SYLLABI FOR DOCTORAL COURSES

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Swedish title Ålder och kardiovaskulär hälsa
English title Age, Ageing and Cardiovascular Health
Course number 5690
Credits 1.5
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Grading Passed /Not passed
Established by The Committee for Doctoral Education
Established 2023-03-20
Purpose of the course The aim of this course is to offer participants interested in vascular diseases an overview of the effect of age and aging on the vascular wall and the clinical readouts. We will go through the spectrum of vascular modifications that characterize healthy aging and those that associates to cardiovascular diseases, from coronary heart disease to vascular pathologies.
Intended learning outcomes Upon completion of the course, the participants should be able to: 1) understand the difference between healthy aging and age related disease; 2) describe the pathophysiology of the most common cardiovascular diseases related to aging; 3) discuss the concept of frailty and 4) show an insight into the application of concept learned in their current and future research
Contents of the course The course will cover an introductory lecture on vascular biology in the elderly from physiology to pathology. It will then cover the manifestations of aging in the heart, large vessels and the brain. One day will be devoted to discuss the concept of frailty and the interventions to de-frail elderly patients
Teaching and learning activities The course will be based on the reverse classroom model. Students will read selected papers in the morning that will be discussed with the teacher in the early afternoon. The student will be asked to prepare questions based on the articles they have read in the morning. The afternoon activities will include lectures, seminars given by a researcher expert in the field and group discussions on selected topics.
Compulsory elements Attendance to the seminars and group work and discussion is mandatory as the discussion is part of the examination. The final written exam is also mandatory.
Examination In order to pass the course, each participant needs to prove that s/he has reached the previously indicated learning outcomes of the course. The final grade (pass or fail) will be based on written exam written exam where the students have to write a short aessay on one topic related to the course content. Please note that the exam will be written at KI during the course hours on the last day of the course.
Literature and other teaching material Jaiswal S, et al. N Engl J Med 2014;371:2488-2498
Franceschi C, Nature Review Endocrinology 2018;14: 576–590
Chirinos J, et al JACC 2019;741237–1263
Kirchenbaum GA, et al. J Immunological Sci. 2019;3: 14-20

Several papers will be read and discussed during the course and will also be part of the literature.
Course responsible Bruna Gigante
Institutionen för medicin, Solna


Bruna.Gigante@ki.se
Contact person