Kursplansdatabas för forskarutbildningskurser
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Kursplansdatabas för forskarutbildningskurser
KURSPLANER FÖR FORSKARUTBILDNINGSKURSER
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| Svensk benämning | Strålbehandling: vår osynliga allierade mot cancer |
|---|---|
| Engelsk benämning | Radiotherapy: Our Invisible Ally Against Cancer |
| Kursnummer | 5625 |
| Antal högskolepoäng | 1.5 |
| Kursansvarig institution | Institutionen för kvinnors och barns hälsa |
| Särskild behörighet | The students are expected to have acquired a basic knowledge of cancer and/or radiation biology during pervious courses. |
| Betygsskala | Godkänd/Icke godkänd |
| Fastställd av | The Committee for Doctoral Education |
| Datum för fastställande | 2022-09-19 |
| Kursens syfte | The course will provide a platform to obtain advanced, cutting-edge pre-clinical and clinical knowledge in the field of radiation therapy. |
| Kursens lärandemål | At the end of the course the participants should be able to:
• reflect upon radiotherapy from the patient’s perspective • describe the properties of different types of ionizing radiation: photons, protons, electrons, and alpha particles • describe the effects of ionizing radiation on different tissues • understand basic radiation therapy dose calculations • be aware of basic principles of when to choose radiotherapy as a treatment for a patient • describe imaging tools used to create target plans • apply principles of radiation protection for patients, self and others • present late complications induced by radiotherapy • elaborate on strategies of how to ameliorate the side effects of radiotherapy • show analytical and critical thinking when discussing problems in the radiation therapy field, beyond what is found in textbooks • connect their own research with topics covered in the course |
| Kursens innehåll | • What is radiotherapy?
• Meet a patient who has undergone radiotherapy • A brief history of radiotherapy • Basic physics of radiotherapy • Why can we use radiation to combat cancer? • Biological effects of radiation • Clinical considerations and uses • Conjugated therapies and radiosensitizers • Radiotherapy delivery options • Radiotherapy-associated complications and their potential treatments • Radiation safety and protection • The future of radiotherapy • Practical sessions (X-ray cell exposure; visit to the Radiotherapy department, KS) • Examination |
| Arbetsformer | For the most part, the course will consist of lectures by experts in the field. In addition, we will have two practical sessions and group exercises. |
| Obligatoriska moment | Attendance is compulsory. Absence will need to be compensated by a written report of an extra assignment in the form of a literature review covering the missed topic. |
| Examination | An oral exam consisting of a PowerPoint presentation and discussion of the group assignments, in which the students will present their solutions on different topics related to the course. Each student will be assessed individually. |
| Kurslitteratur och övriga läromedel | Recommended literature:
Recent Developments in Radiotherapy. Deborah E. Citrin, M.D. Editor Dan L. Longo, M.D. N Engl J Med 2017; 377:1065-1075. doi: 10.1056/NEJMra1608986. Review: Neurological Complications From Therapies for Pediatric Brain Tumors. Thien Nguyen, Sabine Mueller, Fatema Malbari. Front Oncol. 2022; 12:853034. doi: 10.3389/fonc.2022.853034. Review: Cross-translational models of late-onset cognitive sequelae and their treatment in pediatric brain tumor survivors. Noor Z Al Dahhan, Elizabeth Cox, Brian J Nieman, Donald J Mabbott. Neuron 2022; 110(14):2215-2241. doi: 10.1016/j.neuron.2022.04.009. Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain. Osman AM, Sun Y, Burns TC, He L, Kee N, Oliva-Vilarnau N, Alevyzaki A, Zhou K, Louhivuori L, Uhlén P, Hedlund E, Betsholtz C, Lauschke VM, Kele J, Blomgren K. Cell Rep. 2020; 31(9):107699. doi: 10.1016/j.celrep.2020.107699. Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition. Zanni G, Goto S, Fragopoulou AF, Gaudenzi G, Naidoo V, Di Martino E, Levy G, Dominguez CA, Dethlefsen O, Cedazo-Minguez A, Merino-Serrais P, Stamatakis A, Hermanson O, Blomgren K. Mol Psychiatry. 2021; 26(1):322-340. doi: 10.1038/s41380-019-0584-0. |
Kursansvarig |
Adamantia Fragkopoulou Institutionen för kvinnors och barns hälsa 0721563488 adamantia.fragkopoulou@ki.se |
| Kontaktpersoner |
