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Swedish title Hälsoriskbedömning av hormonstörande ämnen
English title Health Risk Assessment of Endocrine Disruptors
Course number 5241
Credits 1.5
Responsible KI department Institutet för miljömedicin
Specific entry requirements
Grading Passed /Not passed
Established by The Committee for Doctoral Education
Established 2020-02-26
Purpose of the course The purpose of the course is to give the student knowledge and understanding of molecular mechanisms and adverse effects of endocrine disruptors as well as of methodologies to study and identify such substances and to assess the health risks.
Intended learning outcomes After the end of the course the student should be able to:
- Describe molecular mechanisms and potential adverse effects of endocrine disruptors
- Explain methodologies to study endocrine disruptors
- Apply methodology for identification of endocrine disruptors according to EU scientific criteria and guidance
- Identify and discuss challenges in health risk assessment of endocrine disruptors
Contents of the course Endocrine disruptors are defined as an exogenous substance or mixture that alters function(s) of the endocrine system and consequently causes adverse health effects in an intact organism, or its progeny, or (sub)populations.
Endocrine disruptors act via hormone receptors and by altering hormone levels and have been implicated in several endocrine-related diseases.
The course will include molecular mechanisms of endocrine disruptors, from molecular initiating events to adverse effects. Methodologies for identification and analysis of the endocrine disruptors will be addressed. Identification of endocrine disruptors based on EU scientific criteria and guidance will be addressed. Attention will be given to future challenges in health risk assessment of endocrine disruptors.
Teaching and learning activities Teaching and learning activities include lectures, exercises and group assignments.
Compulsory elements Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual
task.
Examination Examination is in the form of a written examination and an oral presentation.
Literature and other teaching material Recommended literature in the form of reports and guidance documents from international organisations as well as scientific publications will be provided.
Course responsible Johanna Zilliacus
Institutet för miljömedicin
08 52483544

Johanna.Zilliacus@ki.se

Contact person