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SYLLABI FOR DOCTORAL COURSES

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Swedish title Virala sjukdomar - mekanismer och patogenes
English title Human Viral Diseases: Mechanisms and Pathogenesis
Course number 5237
Credits 1.5
Responsible KI department Institutionen för medicin, Huddinge
Specific entry requirements Ingen
Grading Passed /Not passed
Established by The Committee for Doctoral Education
Established 2020-02-26
Purpose of the course The aim of the course is to enable students to acquire a good knowledge on mechanisms and pathogenesis related to viral infection in humans.
Intended learning outcomes The course should give knowledge of molecular virology with special consideration to the role of virology within medicine. On completion of the course the student is expected to:

- Be able to account for taxonomic subdivision of viruses.
- Be able to account for the most important human pathogenetic viruses.
- Be able to account for the molecular mechanisms of the virus life cycle
- Be able to account for emerging viruses and pandemics
- Be able to account for viral pathogenesis
- Be able to account for virological methods in research
- Be able to account for viral immunology, antiviral therapy and vaccination.
Contents of the course Virus taxonomy, important human pathogenic viruses, virus structure, infection process at cell level and organism level, pathogenesis, epidemiology, molecular interactions between viruses and host cells, genetic stability of viruses, influence on host cell growth control, immune response against viruses, virus vaccines, antiviral drugs, virus vectors for gene therapy
Teaching and learning activities The course will be given over one week (full time). The teaching is mainly through lectures/seminars. The lectures include introduction to the various topics (described above).
Compulsory elements All seminars and lectures. Absence needs to be compensated for in agreement with the course leader. More than one day of absence cannot be compensated for.
Examination Written exam containing open questions.
Literature and other teaching material Handouts given by the lecturers. Reference book: Flint, S. J., Racaniello, V.R., Rall, G.F., Skalka, A.M. and Enquist, L.W.: Principles of Virology, Volume 1: Molecular Biology. 4th edition. ASM Press (2015)
Course responsible Magdalini Lourda
Institutionen för medicin, Huddinge


Magdalini.Lourda@ki.se

Contact person Benedict Chambers
Institutionen för medicin, Huddinge


Benedict.Chambers@ki.se