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SYLLABI FOR DOCTORAL COURSES

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Swedish title Signaltransduktion i hjärnsjukdomar
English title Signal transduction in brain diseases
Course number 1587
Credits 1.5
Responsible KI department Institutionen för neurovetenskap
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2016-10-10
Purpose of the course
Intended learning outcomes Knowledge and understanding: After completion of the course, the graduate student should be able to understand and describe the molecular basis of specific neuropsychiatric and neurodegenerative disorders (cf. below), with particular emphasis on the mechanisms of synaptic plasticity related to these pathological conditions. The student should also be able to understand current therapies, their efficacy and their limits.
Skills and professional attitudes: The students should be able to critically evaluate and discuss advantages and disadvantages of potential interventions on signal transduction processes for the treatment of neuropsychiatric and neurodegenerative disorders.
Contents of the course The course describes alterations in signaling associated to neuropsychiatric and neurodegenerative disorders, including schizophrenia, depression, drug addiction, Parkinson's disease and Alzheimer's disease. The potential relevance of such alterations for the etiology and the therapy of the various diseases will be discussed.
Teaching and learning activities The course will be organised as a series of presentations held by researchers working in various fields of molecular neuroscience and neuropharmacology. There will be four days of lectures and a final fifth day for the examination. Each lecture will consist of two hours of presentation followed by 45 min of discussion between the students and the speaker. Students will receive specific literature to prepare the discussion.
Compulsory elements 1) Discussion: Students will be divided into groups of 4 and each group will be asked to present two questions to discuss with each lecturer at the end of the presentations. 2) Individual written exam on the fifth day. To compensate for absence from a compulsory part the graduate student will have to report on a specific lecture or write an extra exam.
Examination Written examination
Literature and other teaching material Before the start of the course, students will receive two scientific articles selected by the speakers and describing the content of each lecture (a total of about 16 papers). These articles will be used to prepare the discussion and the final exam.
Course responsible Gilberto Fisone
Institutionen för neurovetenskap
0852487375

Gilberto.Fisone@ki.se

Contact person Gilberto Fisone
Institutionen för neurovetenskap
0852487375

Gilberto.Fisone@ki.se