Syllabus database for doctoral courses
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Syllabus database for doctoral courses
SYLLABI FOR DOCTORAL COURSES
Swedish title | Hälsoriskbedömning: Principer och Tillämpningar |
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English title | Health Risk Assessment: Principles and Applications |
Course number | 3125 |
Credits | 1.5 |
Responsible KI department | The institute of Environmental Medicine |
Specific entry requirements | |
Grading | Passed /Not passed |
Established by | The Board of Doctoral Education |
Established | 2018-08-16 |
Purpose of the course | The purpose of this course is to build knowledge and understanding of the scientific method to assess risks to humans of exposure to different types of chemicals.
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Intended learning outcomes | Upon completion of the course, the student should be able to:
-describe the basic concepts and principles of health risk assessment of chemical substances -explain how different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data are used in risk assessment -assess the relevance and reliability of data used in risk assessment -derive health based guidance values such as Acceptable Daily Intake (ADI) based on the data -reflect on the role of health risk assessment in regulatory decision making |
Contents of the course | Health risk assessment of chemicals is the scientific method to assess the risk to humans of exposure to different types of chemical substances, such as pharmaceuticals, environmental pollutants, chemicals in cosmetics, clothing or other everyday products and pesticide residues, food additives and other substances in food.
The course starts off with introducing the concepts in risk assessment, e.g. aims of risk assessment, role of risk assessment in risk analysis (risk assessment, risk management, risk communication), different steps in risk assessment (hazard identification, hazard characterisation, exposure assessment, risk characterisation). It moves on to the different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data that are used in risk assessment. Thereafter it is discussed how the relevance and reliability of the data is assessed, and how different types of evidence are integrated (for example from animal and epidemiological studies). The principles on how to derive health-based guidance values such as Acceptable Daily Intake (ADI) and to derive Margins of Safety values based on the data are exercised. The course then moves on to provide examples of the role of risk assessment in regulatory decision making. Case studies of different types of risk assessments exemplify how research connects to risk assessment activities. The participants will also discuss how their own research can contribute to risk assessments. |
Teaching and learning activities | Teaching and learning activities include lectures, exercises and group assignments. |
Compulsory elements | Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task. |
Examination | Examination is in the form of a written assignment and/or oral presentation. |
Literature and other teaching material | Health risk assessment reports and guidelines from international organisations. | Course responsible |
Anna Beronius The institute of Environmental Medicine anna.beronius@ki.se |
Contact person |
Johanna Bergman The institute of Environmental Medicine johanna.bergman@ki.se Nobels väg 13 17177 Stockholm |