Syllabus database for doctoral courses
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Syllabus database for doctoral courses
SYLLABI FOR DOCTORAL COURSES
Swedish title | Adverse outcome pathways (AOPs)-principer och tillämpningar inom toxikologi och hälsoriskbedömning |
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English title | Adverse outcome pathways (AOPs)-principles and applications in toxicology and health risk assessment |
Course number | 2986 |
Credits | 1.5 |
Responsible KI department | Institutet för miljömedicin |
Specific entry requirements | |
Grading | Passed /Not passed |
Established by | The Board of Doctoral Education |
Established | 2017-03-10 |
Purpose of the course | The purpose of the course is to enable the acquirement of knowledge and understanding in how the concept of Adverse outcome pathways (AOPs) can provide a framework for research in toxicology and for applications for health risk assessment. An AOP is a description of a sequence of events starting with the interaction of a chemical with a biomolecule in a target cell or tissue (molecular initiating event), progressing through key events and ending in an adverse outcome. |
Intended learning outcomes | At the end of the course the student should be able to:
- describe the principles and components of Adverse Outcome Pathways (AOPs) - explain how experimental studies can support the development of AOPs - discuss how AOPs can be used as a central framework for mechanistic toxicity studies, toxicity testing and health risk assessment |
Contents of the course | The course will include the concept and principles of Adverse Outcome Pathways (AOPs). Development and assessment of AOPs. Examples of different AOPs. Application of the AOP concept in toxicological research and health risk assessment. |
Teaching and learning activities | Teaching and learning activities include lectures, exercises and group assignments. |
Compulsory elements | Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task. |
Examination | Examination is in the form of a written assignment and/or oral presentation. |
Literature and other teaching material | Scientific publications and reports from international organisations. | Course responsible |
Johanna Zilliacus Institutet för miljömedicin 08 52483544 Johanna.Zilliacus@ki.se |
Contact person |
Johanna Bergman Institutet för miljömedicin johanna.bergman@ki.se Nobels väg 13 17177 Stockholm |