Kursplansdatabas för forskarutbildningskurser
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Kursplansdatabas för forskarutbildningskurser
KURSPLANER FÖR FORSKARUTBILDNINGSKURSER
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| Svensk benämning | Neurogenetik |
|---|---|
| Engelsk benämning | Neurogenetics |
| Kursnummer | 2600 |
| Antal högskolepoäng | 1.5 |
| Kursansvarig institution | Institutionen för neurobiologi, vårdvetenskap och samhälle |
| Särskild behörighet | |
| Betygsskala | Godkänd/Icke godkänd |
| Fastställd av | The Board of Doctoral Education |
| Datum för fastställande | 2017-03-14 |
| Kursens syfte | The purpose of the course is to introduce the concepts and methodology applied in human genetic studies in general with examples from human diseases in the nervous system and to use this knowledge to prepare and present oral presentations as well as ask and answer questions. The course will also allow interaction between PhD-students with master students in their second year, both with a special interest in neuroscience. A potential purpose for students attending all 6 courses given in sequence (Frontiers Courses in Neuroscience) is also to place Neurogenetics in a greater research context. |
| Kursens lärandemål | I) The student will be able to understand and describe the major differences and uses of human genetic studies of neurogenetic diseases using i) Twin-studies, ii) population based studies, iii) case-control studies, iv) family studies. Students will have an in depth knowledge and understanding of selected neurologic conditions such as Alzheimer disease, trinucleotide repeat disorders, their genetic basis and an insight into the molecular pathogenesis, if known. II) The students will also be able to describe how genetic studies can be used to increase our understanding of the biological basis of neurological conditions. III) The students will be able to contribute substantially to critical evaluation and presentation of scientific articles in the field of neurogenetics. IV) The students will have an understanding of the different genetic techniques and platforms available for studies in human (neurological) conditions.V) The students will have an insight in the application/use of genetic testing for neurological diseases. |
| Kursens innehåll | I) The course will give examples of how different types of genetic studies can help us identify genes involced in the pathogenesis of neurological disease: i) Twin-studies, ii) population based studies, iii) case-control studies, iv) family studies. II) The course will give examples of different gene defects in neurological diseases such as trinucleotide repeats, point mutations, copy number variations, susceptibility genes, rearrangements, transciptional regulation and epigenetics. III) The course will provide an in depth understanding of the genetics of selected neurological diseases and how these genetic dysfunctions help us understand the molecular mechanisms of disease. |
| Arbetsformer | Daily class-room lectures. Time will be allocated for students to prepare a group presentation of a selected topic/genetic neurological disease. The presentation will be on the last day of the course and constitutes the examination. |
| Obligatoriska moment | All lectures/seminars are compulsory and in case of absence, the session can be compensated by a short written report using the literature after agreement with the course director. |
| Examination | The examination will be on the last day of the course and it will consist of i) participating in a group presentation of a selected topic/genetic neurological disease ii) participate as an active audience when other groups have their presentations. Every student will be assessed individually in accordance with the intended learning outcomes of the course. |
| Kurslitteratur och övriga läromedel | The lecturers and course organizer will provide a list and pdfs of recommended scientific articles published in scientific journals as well as recommended weblinks. | Kursansvarig |
Caroline Graff Institutionen för neurobiologi, vårdvetenskap och samhälle 733839399 0733839399 Caroline.Graff@ki.se Bioclinicum J10:20 Visionsgatan4 17164 Solna |
| Kontaktpersoner |
Eva Kallstenius Institutionen för neurobiologi, vårdvetenskap och samhälle 08-52483522 eva.kallstenius@ki.se Linn Öijerstedt Institutionen för neurobiologi, vårdvetenskap och samhälle linn.oijerstedt@ki.se Kalicharan Patra Institutionen för neurobiologi, vårdvetenskap och samhälle kalicharan.patra@ki.se |
