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Swedish title Icke-kodande RNA och cancer
English title Non-coding RNA and cancer
Course number 2583
Credits 1.5
Responsible KI department Institutionen för onkologi-patologi
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2016-12-20
Purpose of the course The course aims to develop students understanding of various methodologies used in RNA research, which is achieved via lectures and problem based learning exercise.
Intended learning outcomes At the end of the course, the students are expected to be able to:
- understand the diversity of non-coding RNAs and their importance in tumorigenesis and tumor progression.
- describe various methodologies for non-coding RNA research, account for applications and apply relevant approaches in their own projects.
Contents of the course Non-coding RNAs are key regulators of gene expression with important impact in many biological processes. Different classes of non-coding RNA are known to play important roles in cancer development and progression. Through short introductory lectures and in-depth discussion of key papers from the recent literature, this course will cover an up-to-date introduction to the biogenesis of diverse non-coding RNAs (including small RNAs and long non-coding RNAs) and their mechanisms of gene regulation, methodologies for non-coding RNA research, expression and function of non-coding RNAs in cancer development, and their potential clinical implications.
Teaching and learning activities The course consists of lectures and problem-based discussions. In addition, the students are required to submit a research proposal on a topic related to non-coding RNA and cancer.
Examination The examination of the course includes problem-based discussions, and reviewing and presenting individual research proposal related to non-coding RNA.
Literature and other teaching material A list of scientific articles in the field of non-coding RNA will be distributed good time in advance of the course as recommended reading.
Compulsory elements The students are expected to attend all lectures and problem-based discussions, as well as to complete all assignments. In the case of absence, the student will be asked to compensate by completing another written assignment given by the course organizer.
Course responsible Weng-onn Lui
Institutionen för onkologi-patologi
08-51773930

Weng-onn.Lui@ki.se

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