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SYLLABI FOR DOCTORAL COURSES

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Swedish title Neural kontroll av inflammation: En introduktion till Bioelektronisk Medicin
English title Neural Control of Inflammation: An introduction to Bioelectronic Medicine
Course number 2957
Credits 1.5
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2016-09-08
Purpose of the course The purpose of this course is to give doctoral students insights into the neural control of homeostasis, particularly the regulation of inflammation, and how engineering, neuroscience, immunology and clinical medicine can come together to find new ways to treat disease.
Intended learning outcomes After the course, the doctoral student will be able to
define prototypical neural circuits that regulate homeostasis
explain the role of inflammation in the pathogenesis of and recovery from autoimmune diseases, cardiovascular diseases and infection
identify the components of the "inflammatory reflex"
discuss regulatory mechanisms for cytokine release
classify different interfaces with the nervous system and the immune system
contrast advantages and drawbacks with major treatment approaches for inflammatory diseases
describe molecular sensors for danger in the immune system and the nervous system
define bioelectronic medicine and explain its potential role in clinical medicine
summarize challenges in engineering and medicine for development of bioelectronic medicine technology
Contents of the course Neural control of organ systems will be discussed in molecular, cellular and clinical perspectives. Special attention will be given to the mechanisms that detect and regulate inflammation. The neurophysiology of vagus nerve stimulation and other treatments that involve interfacing with the nervous system will be reviewed. Progress in neural interfacing and device development within the emerging field of Bioelectronic Medicine will be discussed.
Teaching and learning activities Lectures, a student project group and a student presentation.
Examination Project presentation and written examination.
Literature and other teaching material Relevant articles and other written material will be made available after admission.
Compulsory elements Lectures, project group participation, active participation in presentation and passing the examination is compulsory for "PASS". Limited absence from lectures can be compensated for after individual discussion with the course organizers.
Course responsible Peder Olofsson
Institutionen för medicin, Solna


Peder.Olofsson@ki.se

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