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Swedish title Analys av felkällor i registerbaserad forskning
English title Analysis of bias in register-based research
Course number 2864
Credits 1.5
Responsible KI department Institutet för miljömedicin
Specific entry requirements Knowledge equivalent to Epidemiology I and Biostatistics I or corresponding courses.
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2016-03-31
Purpose of the course The course introduces participants to different sources of bias that may have an impact on the findings arising from register-based studies.
Intended learning outcomes After successfully completing this course you as a student are expected to be able to:

- Identify and explain common forms of biases.
- Reason about potential sources of bias in register-based research.
- Evaluate how different sources of bias may influence the findings arising in different register-based studies.
- Apply the knowledge attained to identify and reason about potential biases in your own research.

Learning outcomes are classified according to Bloom¿s taxonomy: knowledge, comprehension, application, analysis, synthesis, and evaluation (Bloom, 1956, extended by Anderson and Krathwohl, 2001).
Contents of the course The course focuses on different sources of bias in register-based studies. Bias can be introduced and occur related both to the exposure and the outcome, as well as confound any association. The course introduces the participants to aspects that can be kept in mind to get a better understanding of when and how bias can occur, as well as the magnitude and possible direction of bias.
Teaching and learning activities Different strategies for teaching and learning, such as lectures, group and individual assignments, and roundtable discussions as well as a panel discussion, will be used. The course focuses on active learning, i.e. putting knowledge into practice and critically reflecting upon the knowledge, rather than memorising facts. Participants are expected to actively participate in all parts of the course.
Compulsory elements The individual examination (summative assessment).
Examination To pass the course, the intended learning outcomes have to be achieved. The way of grading is passed/not passed. The examination consist of an individual examination performed as a home examination. The examination is viewed as contributing to the development of knowledge, rather than a test of knowledge. Students who do not obtain a passing grade in the first examination will be offered a second examination within two months of the final day of the course. Students who do not obtain a passing grade at the first two examinations will be given top priority for admission the next time the course is offered.
Literature and other teaching material Suggested reading

Ludvigsson JF, Almqvist C, Bonamy AE, Ljung R, Michaëlsson K, Neovius M, Stephansson O, Ye W.
Registers of the Swedish total population and their use in medical research. European Journal of Epidemiology 2016 Jan 14. [Epub ahead of print]. PMID: 267696091-12.

Ludvigsson JF, Otterblad-Olausson P, Pettersson BU, Ekbom A: The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research. European Journal of Epidemiology 2009,24:659-67.

Böhlmark A, Lindquist MJ. Life-cycle variations in the association between current and lifetime income: Replication and extension for Sweden. Journal of Labor Economics 2006;24:879-96.

Other scientific papers on specific topics will be distributed during the course.
Course responsible Karin Modig
Institutet för miljömedicin
08-524 801 53

Karin.Modig@ki.se

Contact person Johanna Bergman
Institutet för miljömedicin


johanna.bergman@ki.se

Nobels väg 13

17177
Stockholm