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Svensk benämning Neurodegenerativa sjukdomar II - cellulära och molekylära mekanismer
Engelsk benämning Neurodegenerative Disorders II - Cellular and Molecular Mechanisms
Kursnummer 2630
Antal högskolepoäng 1.5
Kursansvarig institution Institutionen för neurobiologi, vårdvetenskap och samhälle
Särskild behörighet The course is a continuation of the course Neurodegenerative disorders I, From molecule to treatment, but it can also be taken as a separate course, provided the participant has in other ways achieved the learning outcomes of that course.
Betygsskala Godkänd/Icke godkänd
Fastställd av The Board of Doctoral Education
Datum för fastställande 2018-03-16
Kursens syfte The purpose of the course is to provide a deeper understanding of neurodegenerative disorders, focusing on molecular mechanisms and techniques used for studying these, as well as treatment strategies.
Kursens lärandemål The student should be able to:
- understand and critically evaluate relevant cellular and molecular pathophysiological mechanisms of neurodegenerative disorders such as stroke, Alzheimer disease, frontotemporal dementia, Lewy body disease, Parkinson´s disease, multiple sclerosis, amyotrophic lateral sclerosis, and the mechanisms of current and/or possible future treatments.
- understand and perform important methods and assays for studying mechanisms behind neurodegenerative disorders, and discuss the results, taking into account the limitations of the assays.
- discuss the present disease models, propose alternative models, and critically evaluate these models from the perspectives of a) clinical picture, b) disease mechanisms, and c) treatment mechanisms.
Kursens innehåll The course addresses topics in basic and clinical research on neurodegenerative disorders. The focus will be on a deeper understanding of cellular and molecular mechanisms, and the techniques to study them. To this end, the students will learn about some powerful techniques that can be used for studying neurodegeneration, subcellular localization, and elucidation of pathogenic pathways.
Arbetsformer The course runs daytime for 1 week full-time with some key lectures by invited scientists, laboratory practicals, and discussions in small groups and the entire class.
Obligatoriska moment The student is obliged to attend 80% of the lectures, all laboratory practicals, and the exam (including the group discussion after the exam). Students that are absent from the practicals and/or more than 20% of the lectures will have to submit a written presentation of the subjects missed.
Examination Oral examination followed by group discussions on the examination questions, and a general discussion between all participants.
Kurslitteratur och övriga läromedel Scientific articles and hand-outs distributed by the course organizers and lecturers.
Kursansvarig Sophia Schedin Weiss
Institutionen för neurobiologi, vårdvetenskap och samhälle


sophia.schedin.weiss@ki.se

Kontaktpersoner Lars Tjernberg
Institutionen för neurobiologi, vårdvetenskap och samhälle


Lars.Tjernberg@ki.se

Sophia Schedin Weiss
Institutionen för neurobiologi, vårdvetenskap och samhälle


sophia.schedin.weiss@ki.se