Syllabus database for doctoral courses
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Syllabus database for doctoral courses
SYLLABI FOR DOCTORAL COURSES
| Swedish title | Mesenkymala stamcellers biologi och kliniska potential. |
|---|---|
| English title | Mesenchymal stem cells -biology and clinical potential. |
| Course number | 2652 |
| Credits | 2.0 |
| Responsible KI department | Institutionen för laboratoriemedicin |
| Specific entry requirements | None. |
| Grading | Passed /Not passed |
| Established by | The Board of Doctoral Education |
| Established | 2015-12-16 |
| Purpose of the course | |
| Intended learning outcomes | After the completed course, the student will be able to describe the basics of stem cell biology and transplantation and a number of novel technologies and approaches in mesenchymal stem cell research and regenerative medicine. The student can demonstrate an interdisciplinary understanding of central concepts in mesenchymal stem cell science and critically evaluate different methods and techniques used. The student will be able to extract and integrate information from state-of-the-art lectures in combination with overview articles and literature searches on the internet within the research field. |
| Contents of the course | The course covers key concepts in translational research on mesenchymal stem cells from the laboratory to the patient in the clinic. This includes a general overview of stem cell biology, transplantation immunology, mesenchymal stem cell history, sources, homing and circulation and interaction with the immune system. Experts will give an advanced summary of the latest events in the mesenchymal stem cell field. The student will be required to take an active part, contribute and value discussions on ethical dilemmas in the transplantation area and in workshops on relevant topics in the mesenchymal stem cell-field. Networking with students and speakers is highly encouraged in this course. |
| Teaching and learning activities | The pedagogic framing of this course is based on lectures with corresponding review papers. The course includes workshops with illustrative predicaments where the students are required to take an active part in the discussions. Group discussions and workshops will be conducted where the students discuss and integrate information from the lectures and review papers. The students prepare and present their examination task in a written report that is handed in after the course. |
| Compulsory elements | The lectures, workshops and discussions are mandatory. Compensation according to the instructions of the course director. |
| Examination | Individual written project report that will be performed and handed in at the end of the course. The individual performance of each student will be evaluated separately. |
| Literature and other teaching material | The course literature will consist of recent original and review papers on selected topics within the field of stem cell transplantation as well as the latest articles from the expert lecturers. Handouts from the lecturers will also be included. Examples of review articles: - Ilic D. Stem cell based therapy-where are we going? Lancet. 2012; 379(9819):877-8. - Trounson A. Clinical trials for stem cell therapies. BMC Med. 2011; 9:52. - Chien, K.R. Regenerative medicine and human models of human disease. Nature. 2008; 453(7193):302-5. - Ankrum J. Mesenchymal stem cell therapy: Two steps forward, one step back. Trends Mol Med. 2010; (5):203-9. Keating A. Mesenchymal stromal cells: new directions. Cell Stem Cell. 2012; 10(6):709-16. - Le Blanc K. Multipotent mesenchymal stromal cells and the innate immune system. Nat Rev Immunol. 2012; 12(5):383-96. Examples of webpages: http://stemcells.nih.gov/ http://www.explorestemcells.co.uk/ |
Course responsible |
Cecilia Gotherstrom Institutionen för klinisk vetenskap, intervention och teknik 08-58581487 070-4712300 Cecilia.Gotherstrom@ki.se Klinisk Immunologi F79 Karolinska Universitetssjukhuset Huddinge 14186 Stockholm |
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