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SYLLABI FOR DOCTORAL COURSES

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Swedish title Infektioner och cancer/Tumörvirologi
English title Infections and cancer/Tumour virology
Course number 1592
Credits 1.5
Responsible KI department Department of Oncology-Pathology
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2015-09-17
Purpose of the course
Intended learning outcomes At the end of the course the students should be able to:

- Identify and discuss the mechanisms of malignant transformation by DNA and RNA viruses
- Identify and discuss the mechanisms by which bacteria infections can contribute to tumor development
- Discuss the current status of vaccines against tumor viruses
- Identify and discuss the issues related to pro-carcinogenic viruses/bacteria and immune defense as well as vaccines and treatment of virus- and bacteria- induced tumors
Contents of the course The course will present the virus groups presently known to be involved in the development of human cancers, such as Human Papilloma viruses, Hepatitis B and C virus, Epstein-Barr virus, and HHV-8 as well as the major tumors related to these viruses. In addition, mechanisms of bacterial-induced carcinogenesis and bacterial agents involved in cancer development will be addressed. Specific aspects of tumor virology such as mechanisms of viral carcinogenesis, history of tumor virology, tumor viruses and immune defense as well as vaccines against tumor viruses and treatment of virus-induced tumors will also be presented.
Teaching and learning activities The course will be organized as lectures held by prominent researchers within the field, who will discuss the general concepts of infection and cancer, as well as present cutting edge research and relevant issues that still need to be resolved within the field. Student oral presentation of a scientific paper will complete the teaching and learning activities.
Compulsory elements Attendance to the lectures and the oral presentations are compulsory. In special cases, with limited absence, the student can compensate with a written report.
Examination The course assessment will be based on: i) a written examination, and ii) presentation of a scientific article in a format of a journal club.
Literature and other teaching material The students will be provided before the starting of the course with relevant and recent review articles that should be read before the start of the course. They will also receive the scientific papers that will be presented as part of the course assessment.
Course responsible Torbjörn Ramqvist
Department of Oncology-Pathology
0851779634

Torbjorn.Ramqvist@ki.se

Contact person Teresa Frisan
Department of Cell and Molecular Biology
08-52486385

Teresa.Frisan@ki.se

Berzelius väg 35

S-17177
Stockholm
Tina Dalianis
Department of Oncology-Pathology
0851770000

Tina.Dalianis@ki.se