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SYLLABI FOR DOCTORAL COURSES

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Swedish title Epigenomikens metoder, mekanismer och tillämpning i hälsa och sjukdom
English title Epigenomics methods, mechanisms and application to disease and development
Course number 2804
Credits 1.5
Responsible KI department Institutionen för cell- och molekylärbiologi
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2014-09-03
Purpose of the course
Intended learning outcomes After the completed course, the participants will be able to describe the basic methods and mechanisms underlying epigenetic regulation in non-disease cases and compare and relate these to dysregulation in diseases. The participants will be able to describe and critically evaluate the weaknesses and strengths of the different methods and technologies used in genome-wide epigenomic regulation studies.
Contents of the course Epigenetic regulation in non-disease cases and dysregulation in diseases at individual locus level as well as on genome-wide level including DNA methylation, histone modification, non-coding RNA interaction with DNA and histones. Understanding development and disease principles through epigenetic technologies.
Teaching and learning activities The course consists of lectures, discussion and seminars.
Compulsory elements The discussions and seminars are compulsory. Absence from compulsory parts is compensated according to the instructions from the course leader.
Examination The students will be examined for knowledge and skills, individually based on the active participation in discussions and groupwise with seminar presentations.
Literature and other teaching material Genetic databases and recent articles.
Course responsible Matti Nikkola
Institutionen för cell- och molekylärbiologi


Matti.Nikkola@ki.se

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