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SYLLABI FOR DOCTORAL COURSES

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Swedish title Autofagi i hälsa och sjukdom
English title Autophagy in health and disease
Course number 2769
Credits 1.5
Responsible KI department Institutionen för cell- och molekylärbiologi
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2014-03-04
Purpose of the course
Intended learning outcomes When the students have passed the course, they will be able to describe the molecular mechanism of protein degradation by autophagy and how this relates to human diseases such as cancer and neurodegenerative disorders. The students will also be able to design experiments for studying autophagy and to critically evaluate data obtained with these techniques.
Contents of the course This course covers the molecular mechanism underlying autophagy and its role in human diseases. Extra attention will be paid to experimental methods to study autophagy. We will discuss the relation of autophagy to human diseases, in particular to cancer and neurodegenerative disorders. We will also pay attention to its central role in intracellular proteolysis and cross-talk with other proteolytic systems. The course will be given by the course organizers and several renowned international researchers working on various aspects on autophagy. At the end of the course, there will be a mini-symposium in which researchers will present their ongoing research on autophagy and related topics.
Teaching and learning activities The learning modes used in the course include lectures, research seminars and a mini-symposium. Every student will present a recent publication in a journal club. Students will have lunch meetings with the invited speakers and will also be encouraged to actively participate in the course. There will be ample time for discussions after the lectures and research seminars.
Compulsory elements The lectures, seminars and journal club presentations are compulsory. Compensation according to the instructions of the course director.
Examination Examination is based on the journal club presentation and discussions. Every student will be at one occasion presenting a paper that has been selected by the organizers and at another occasion will be an opponent when a fellow student is presenting a selected paper. The student's performance at these two occasions combined with general active participation in the course will be the basis for the final assessment.
Literature and other teaching material Recent original and review articles.
Course responsible Matti Nikkola
Institutionen för cell- och molekylärbiologi


Matti.Nikkola@ki.se

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