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SYLLABI FOR DOCTORAL COURSES

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Swedish title Epigenomik: metoder och tillämpningar i sjukdom och utvecklingsbiologi
English title Epigenomics: methods and applications to disease and development
Course number 2665
Credits 1.5
Responsible KI department Institutionen för cell- och molekylärbiologi
Specific entry requirements
Grading Passed /Not passed
Established by The Board of Doctoral Education
Established 2012-09-11
Purpose of the course
Intended learning outcomes After the completed course, the participants will be able to describe central epigenetic concepts and mechanisms and relate these to genome-wide applications, in the study of disease and development. The participants will be able to describe and critically evaluate the weaknesses and strengths of different technologies used in epigenomic studies.
Contents of the course Central concepts, mechanisms and methods of epigenetics, such as DNA methylation and histone modifications, in a genome-wide perspective utilizing analytical methods such as bisulphite sequencing, MeDIP and ChIP-Seq. Understanding development and disease through genomic technologies focusing on epigenetic states as determinants of gene regulation.
Teaching and learning activities The course consists of lectures, discussion and seminars, and the use of an internet-based learning platform.
Compulsory elements The discussions and seminars are compulsory. Absence from compulsory parts is compensated according to the instructions from the course leader.
Examination The students will be examined for knowledge and skills, individually based on the active participation in discussions and groupwise with seminar presentations.
Literature and other teaching material
Course responsible Matti Nikkola
Institutionen för cell- och molekylärbiologi


Matti.Nikkola@ki.se

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