Course catalogue doctoral education - VT20

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Title Cardiovascular Research - an overview of the process of atherosclerosis
Course number 3133
Programme Kardiovaskulär forskning
Language English
Credits 1.5
Date 2020-05-11 -- 2020-05-15
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Purpose of the course Atherosclerosis will be discussed from the molecular, cellular, genetic, clinical and epidemiological viewpoints. Therefore, participants with a medical background will have the possibility to be more exposed to experimental work and, conversely, participants with a non-medical background will be enabled to obtain good knowledge of distinct clinical manifestations of atherosclerosis. This will be useful for, among others, bioinformaticians in the field. In addition, the course gives the participants the possibility to network with other students in the cardiovascular field.
Intended learning outcomes The participant should be able to:
1. Relate risk factors with the pathology of atherosclerosis
2. Discuss the development of the atherosclerotic lesion on cellular and molecular level
3. Motivate the use of different models (in vitro-, epidemiological, animal model) to study atherosclerosis and apply them to a given project.
Contents of the course Atherosclerosis will be discussed from the molecular, cellular, genetic, clinical and epidemiological viewpoints. Topics to be covered include discussions of the roles of the following in atherosclerosis: lipids and lipoproteins; oxLDL; thrombosis; plaque stability; inflammation; innate and adaptive immunity; proteinases; blood pressure; and diabetes/insulin resistance. Examples of in vitro and animal models as well as clinical studies will be discussed.
Teaching and learning activities Lectures, project group, presentation by participants.
Compulsory elements Examination is compulsory to pass the course.
Examination To pass the course, the participant has to:
1) Give a presentation in a seminar and to be able to discuss the different aspects of atherosclerosis with the course leader and the other participants.
2) To be able to discuss the other participants' presentations.
3) Pass a written exam recapitulating the course's content.
Literature and other teaching material Relevant state of the art articles in the field of atherosclerosis published in high impact journals, e.g. NJM, Nature, Circulation, and EJH.
Number of students 8 - 30
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant’s doctoral project (according to written motivation), 2) start date of doctoral studies (priority given to earlier start date)
More information This course has previously been given with course number 1551.
Additional course leader Maria Jose Forteza (maria.forteza.de.los.reyes@ki.se) Angela Silveira (angela.silveira@ki.se)
Latest course evaluation Course evaluation report
Course responsible Maria Forteza de los Reyes
Institutionen för medicin, Solna
0704608018
maria.forteza.de.los.reyes@ki.se

Sveavägen, 164K

11346
Stockholm
Contact person Angela Silveira
Institutionen för medicin, Solna
08-51773224
Angela.Silveira@ki.se


Daniel Ketelhuth
Institutionen för medicin, Solna

Daniel.Ketelhuth@ki.se