Course catalogue doctoral education - VT20

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Title Basic Immunology
Course number 3139
Programme Allergi, immunologi och inflammation (Aii)
Language English
Credits 3.0
Date 2020-02-24 -- 2020-03-20
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements Basic knowledge of cell and molecular biology (as an example - to be able to account for the basics of "translation", "G1 phase", "splicing", "endocytosis" (without necessity for molecular details)).
Purpose of the course The student will 1) learn basic concepts in Immunology, 2) get an overview of the various immune cell types and their function and development, and 3) meet the Immunology faculty of Karolinska Institutet. This course is a good starting point for more advanced/thematically focused courses in Immunology. Nevertheless, while this course does not expect any prior education in Immunology, basic immunological concepts will be discussed in depth and detail. Therefore, the course is not only directed at immunology novices, but also at students that wish to broaden and deepen their current general immunological knowledge.
Intended learning outcomes To understand basic principles of innate and adaptive immunity, and how different components of the immune system cooperate.
Contents of the course The course is separated into two parts. In part 1 we discuss basic immunological concepts underlying innate and adaptive immune responses. In part 2 we revisit and discuss these concepts in the context of disease. More specifically, in part 1 we will discuss development and function of key cell types mediating immune responses, pathogen recognition by cells of the innate immune system, generation of antigen receptor repertoires, principles of self/non-self discrimination and immunological tolerance, and mechanisms of humoral and cellular immune responses. In part 2 this knowledge will be applied to more clinical contexts such as defense against infection, autoimmune diseases, allergic diseases, tumors, or transplantation.
Teaching and learning activities This is a full-time course, which consists of 2 parts. The first part will take four full days and one half-day of lectures and work on group assignments. The second part will follow after a teaching-free period of several weeks and will take 3 full days. The purpose of dividing the course into two parts is that the participants should have time to thoroughly study the literature from part 1 (fundamental immunological mechanisms) before teaching and learning of more applied immunology in part 2 starts. Considering the substantial literature requirement plus work on the assignments, we estimate that an extra 2.5 days of self-studying is needed during the teaching free period.
Compulsory elements Lecture attendance and submission of all course assignments is compulsory.
Examination The course assignments must be satisfactory completed. The students will be required at least 95% attendance, and active participation in lectures and contribution to other course activities to pass the course. A single missed day of the course can be tolerated, but the student will be asked to work on an additional individual assignment based on the topic(s) of this day.
Literature and other teaching material The course textbook (Abul Abbas and Andrew Lichtman: Basic Immunology) will be handed out at or before the course start.
Number of students 12 - 30
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information This is a full-time course, which consists of 2 parts. The first will take four full days (February 24th-28th) and one half-day of lectures and work on group assignments. The second part will follow after a teaching-free period of several weeks and will take 3 full days (March 17-19). Considering the substantial literature requirement plus work on the assignments, we estimate that an extra 2.5 days of self-studying is needed during the teaching free period. Lectures will mainly take place at the Center for Molecular Medicine (CMM).

Part 1:
Feb 24 (Mon) - 9:00-17:00
Feb 25 (Tue) - 9:30-17:00
Feb 26 (Wed) - 9:00-17:00
Feb 27 (Thu) - 9:00-17:00
Feb 28 (Fri) - 9:00-12:00

Part 2:
Mar 17 (Tue) - 9:30-17:00
Mar 18 (Wed) - 9:00-17:00
Mar 19 (Thu) - 9:30-17:00
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Taras Kreslavskiy
Institutionen för medicin, Solna

taras.kreslavskiy@ki.se
Contact person Taras Kreslavskiy
Institutionen för medicin, Solna

taras.kreslavskiy@ki.se


Carmen Gerlach
Institutionen för medicin, Solna

carmen.gerlach@ki.se