Course catalogue doctoral education - VT20

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Title Advanced cancer biology
Course number 3024
Programme Tumörbiologi och onkologi (FoTO)
Language English
Credits 3.0
Date 2019-08-27 -- 2019-12-17
Responsible KI department Institutionen för mikrobiologi, tumör- och cellbiologi
Specific entry requirements Basic course in tumour biology and oncology.
Purpose of the course The course aims to provide advanced, cutting edge pre-clinical and clinical knowledge in the field of cancer biology.
Intended learning outcomes At the end of the course the students should:
- Have acquired an updated overview of the cutting edge research activities within the fields of cell- and tumor biology.
- Be able to show analytical and critical thinking when discussion advanced problems in cell- and tumor biology, beyond what is found in text books, and evaluate the relevance of the topics presented in the context of their own research activities and PhD studies.
- Be able to discuss important aspects of tumor biology, including apoptosis, cell cycle, cancer stem cells, differentiation, virus and bacteria-associated cancer, tumor immunology and effects of chronic inflammation in carcinogenesis, cancer genetics and epigenetics, transcriptomics, proteomics and metabolomics of cancer, tumor microenvironment, angiogenesis, metastasis, tumor heterogeneity and development of new treatments as well as key issues in clinical cancer research.
Contents of the course The lecturers will give a comprehensive and pedagogical overview of the research area as well as an in-depth discussion of their own research, related, but not limited, to the following topics: apoptosis, cell cycle, cancer stem cells, differentiation, virus and bacteria-associated cancer, tumor immunology and effects of chronic inflammation in carcinogenesis, cancer genetics and epigenetics, transcriptomics, proteomics and metabolomics of cancer, tumor microenvironment, angiogenesis, metastasis, tumor heterogeneity and development of new treatments as well as key issues in clinical cancer research.
Teaching and learning activities The course will consist of about 20 lectures, with approximately 45 minutes per lecture, at least once a week during one semester.
Each lecture will be followed by an open discussion between the students and the invited speaker led by one of the course organizers: this format will provide time for highlighting key issues within the specific topic and will enhance the possibility for the students to expand their networking activities due to direct contact with experts in the field.
To increase the learning process and to stimulate the reflection on the course topic, the students will be required to study the most recent literature, still not present in the text books within the presented fields, prior to each seminar. Throughout the course period, the course organisers will have regular meetings with the students to follow up the learning process of each individual participant as well as to receive feedback from the students.
Compulsory elements Attending the lectures and the written essay are compulsory. Missed seminars can be compensated by other activities after discussion with the course leader.
Examination The students have to show that the intended learning outcomes of the course are reached. This will be individually assessed during the participation in the informal discussions after the seminars and on the basis an individual written assessment, in form of a project description where one or more topics presented during the course should be integrated within the student own research project (Max one and half A4 page, stating: the objective of the project, a brief description of the research plan, and the significance). The project description should be handed in maximum three weeks after the completion of the course to the organizers.
Literature and other teaching material 1. Weinberg, Robert A. The biology of cancer. Garland Science, Taylor and Francis group, 2007, selected
parts
2. Scientific papers and/or review articles discussing recent advance in the topics presented
Number of students 8 - 25
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information The course is organized to contain approximately 20 lectures of 45 min plus 15 min discussion, held once per week during the semester by invited national and international prominent researchers. All lectures are held at the Biomedicum, Solnavägen 9, in seminar rooms at the 3rd (entrance) floor, KI Solna Campus Tuesdays at 1 pm, unless else stated.
In addition to the lectures, there will be an exam, which will consist of writing a small project, where one or more topics presented during the seminars should be integrated within your research project. The exam is to be handed in three weeks after the end of the course.
Additional course leader Main organizer of the course: Lars-Gunnar Larsson, Lars-Gunnar.Larsson@ki.se.
Co-organizers: Galina Selivanova, Galina.Selivanova@ki.se, Margareta Wilhelm, Margareta.Wilhelm@ki.se
Latest course evaluation Course evaluation report
Course responsible Lars-Gunnar Larsson
Institutionen för mikrobiologi, tumör- och cellbiologi

lars-gunnar.larsson@ki.se
Contact person Lars-Gunnar Larsson
Institutionen för mikrobiologi, tumör- och cellbiologi

lars-gunnar.larsson@ki.se