Course catalogue doctoral education - VT20

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Title Extracellular Vesicles: Progress Towards Diagnostics and Therapy
Course number 3175
Programme Utveckling och regeneration (DevReg)
Language English
Credits 2.0
Date 2019-10-07 -- 2019-10-11
Responsible KI department Institutionen för laboratoriemedicin
Specific entry requirements
Purpose of the course It is only in the past decade that extracellular vesicles (EVs) have been discovered to mediate essential biological processes and cell-cell communication in both health and disease. In addition to characterizing their roles in vivo, these findings have also given rise to unique strategies to treat and diagnose disease. The goal of this course is to expand student's knowledge of EV diversity, biological function and potential applications.
Intended learning outcomes After the course is completed, the student will:
-Be able to describe the basics of EV biology and function, as well as a number of novel technologies for EV isolation and characterization.
-Gain the skills necessary to critically evaluate publications and methods used in the EV field.
-Gain an appreciation for the breadth and relevance of the EV field at present and the questions that are yet to be addressed.
Contents of the course The course will cover key developments in EV biology, function and clinical application. This will begin with an introduction to EV diversity and biogenesis, as well as important examples of their in vivo roles in health and disease. It will include an overview of the most important methods used for EV isolation and characterization. Finally, we will discuss the latest strategies for utilizing EVs as tools in diagnostics and the treatment of disease. Students will play an active role in discussions with experts, as they give summaries of the latest findings in the EV field.
Teaching and learning activities This course will primarily consist of interactive lectures with corresponding review papers. The information gained from these will be used for small group discussions and presentations, where the students will be required to take part in assessing the progress and pitfalls within the field. The examination will be a written report that is handed in after the course.
Compulsory elements Students will be required to attend the lectures and discussions held during the course. The examination must be handed in within one week of course completion. Absence from any component must be compensated for by individual written assignments on the topics missed
Examination A written project report, consisting of two A4 pages covering one of the three topics provided by the course leaders, is expected to be handed in within one week of the course ending. We will also evaluate individuals for their contributions to group discussions and presentations. These elements will be evaluated for each student's understanding of the central concepts in EV biology, function and clinical application.
Literature and other teaching material The course literature will consist of research and review articles on selected topics within the field of extracellular vesicles, as well as the latest articles from the expert lecturers. Printouts from the lectures will also be available.
Number of students 8 - 20
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information The course will be held from 9:30am to 5:30 pm. It will be held in the conference room ""Cellen"" in the Novum building on the Flemingsberg campus of Karolinska Institutet; Hälsovägen 7, 4tr.
Additional course leader The course leaders are Daniel Hagey (daniel.hagey@ki.se) and André Görgens (andre.gorgens@ki.se), while the contact person and supervisor is Samir El Andaloussi (samir.el-andaloussi@ki.se).
Latest course evaluation Not available
Course responsible Daniel Hagey
Institutionen för laboratoriemedicin

Daniel.Hagey@ki.se
Contact person Samir El-Andaloussi
Institutionen för laboratoriemedicin

Samir.El-Andaloussi@ki.se