Course catalogue doctoral education - VT20

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Title Medical developmental biology
Course number 3081
Programme Utveckling och regeneration (DevReg)
Language English
Credits 1.5
Date 2019-08-19 -- 2019-09-06
Responsible KI department Institutionen för klinisk vetenskap, intervention och teknik
Specific entry requirements
Purpose of the course The main purpose of the course is to acquire a better understanding of issues, including ethical ones, in developmental and stem cell biology with direct implications for human development and disease. Furthermore, the course will expose the students to international collaboration and provide an opportunity to build an international network.
Intended learning outcomes After the course the doctoral student is expected to be able:
- To fully understand and review the basic biology and definitions of embryonic and fetal stem cells,
- To understand and review the most fundamental genetic and epigenetic/transcriptional regulatory mechanisms guiding the development of the essential organs,
- To understand and review the basic principles of regenerative medicine and perinatal physiology.
Contents of the course To achieve a better understanding of embryonic and fetal development, and to provide better healthcare for newborns and children, it is necessary to understand the development in basic research to be able to more rapidly apply such knowledge in clinical care. In this course, world-leading scientists in the fields of developmental biology, stem cell research, and regenerative medicine, will discuss the molecular mechanisms, cell biology, genetics and epigenetics of development in general and more specifically in a wide variety of organs, with a particular bias towards human development and disease. The nature of the course is translational and provide a wide range of knowledge from transcriptional mechanisms to basic physiology, ethics and patient care.
Teaching and learning activities The course is based on lectures from morning to lunch by prominent lecturers. There are practical workshops and clinical visits in the afternoons. The course is considered demanding and requires full-time presence and attention.
Compulsory elements Full presence is absolutely required. Necessary absence will be regulated with the course leader and given as extra tasks.
Examination Every student needs to make either a fifteen minute individual presentation or to present their projects by poster presentation. The oral and poster presentations are examined by at least four course leaders and the participants receive immediate feedback directly from the course leaders/examiners. Further feedback is given continuously throughout the course. Every student will in addition write a report that is handed in for evaluation at the end of the course. All students are also required to peer-review another student's examination report. The individual performance of each student will be evaluated separately.
Literature and other teaching material Recommended literature:
Pediatrics and Perinatology. The Scientific Basis. Ed. P Gluckman & MA Heyman
Two review or research articles per lecture (c:a 20 lectures, 40 articles) to be listed by the lecturers.
Number of students 15 - 34
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information This is an international exchange course in Medical Developmental Biology, a.k.a. Developmental and perinatal biology, with University of Toronto (U of T) that has been running since 1996. This year the course will be held in Stockholm with numerous distinguished speakers (from U of T and KI) and advanced workshops. The course covers everything from basic research on stem cells and early embryonic development to clinical aspects of pregnancy, early childhood, epigenetic and ethics.

The course is a full time course during the week of 19-23rd of August with extensive program including lectures, interactive practical workshops, special lectures, social networking, poster and oral research presentations by students. A written report should be written and undergone peer-review in the following two weeks with final end of the course on the 6th of September.
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Fredrik Lanner
Institutionen för klinisk vetenskap, intervention och teknik

fredrik.lanner@ki.se
Contact person Ola Hermanson
Institutionen för neurovetenskap
468-5248-7477
Ola.Hermanson@ki.se


Fredrik Lanner
Institutionen för klinisk vetenskap, intervention och teknik

fredrik.lanner@ki.se