Course catalogue doctoral education - HT19

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Title Clinical achievements of reproductive medicine
Course number 2291
Programme Utveckling och regeneration (DevReg)
Language English
Credits 1.5
Date 2019-09-02 -- 2019-09-06
Responsible KI department Institutionen för klinisk vetenskap, intervention och teknik
Specific entry requirements
Purpose of the course The purpose of the course is to enable doctoral students to obtain a basic understanding of the biological processes involved in human reproduction. Experts in the field will provide with a fresh overview of clinical and pre-clinical research aiming at development of novel treatment possibilities but also discussing their current limitations.
Intended learning outcomes The learning outcomes of this course are that at the conclusion of this course students should be able to show a comprehensive view of key factors involved in reproductive biology and the processes involved in fertilization and implantation. Additionally, at the end of the course students will be able to perform a critical assessment of reported achievements on reproductive medicine and their current clinical possibilities and limitations.
Contents of the course Contents: Biology of the gametes, fertilization and early embryo development Normal and pathological implantation, early pregnancy loss, ectopic pregnancy, repeated miscarriage In vitro spermatogenesis and oocyte maturation Clinical investigation and therapeutic approach on female and male infertility Genetics in infertility Gonadal dysgenesia Stem cells research Assisted reproduction techniques (ART) In vitro systems and cultures Cloning. Somatic cell nuclear transfer Clinical aspects of fertility preservation Cryobiology systems for fertility preservation Pre-implantation genetic diagnosis Epigenetics in assisted reproduction Experimental reproductive tissue transplantation procedures: -ovarian and testicular tissue transplantation -transplantation of the uterus
Teaching and learning activities Lectures, seminars/discussions and laboratory demonstrations.
Compulsory elements All teaching activities, including the laboratory sessions, the lectures and the assessments, are obligatory. In case of not attendance to the activities, students should produce a literature work related with the subject of the missing activity upon agreement with the course organizer.
Examination Written examination and general group discussion of relevant parts of the examination.
Literature and other teaching material Recommended literature: Textbook of Assisted Reproductive Techniques, Fourth Edition. David K. Gardner, Ariel Weissman, Colin M. Howles, Zeev Shoham. Informa, 2012. Clinical Gynecologic Endocrinology and Infertility. Marc A. Fritz and Leon Speroff. Wolters Kluwer, 2010. Infertility; Julius Hreinsson, Lars Hamberger, Thorir Hardarson, Studentlitteratur, 2005 New micromanipulative techniques in reproductive biology. Thesis dissertation, Karolinska Institutet. José Inzunza Stockholm, 2003 (Stockholm: Karolinska University Press). Rodriguez-Wallberg KA, Oktay K. Fertility preservation during cancer treatment: clinical guidelines. Cancer management and research, 2014 Mar 4;6:105-117.
Number of students 8 - 12
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information
Additional course leader
Earlier evaluation of the course Evaluation report
Course responsible Kenny Rodriguez-wallberg
Institutionen för onkologi-patologi
0858580000
kenny.rodriguez-wallberg@ki.se

Reproduktionsmedicin
Karolinska Universitetssjukhuset Huddinge
141 86
Stockholm
Contact person Jose Inzunza
Institutionen för biovetenskaper och näringslära
08-585 850 93
Jose.Inzunza@ki.se

Hälsovägen 7, Novum

141 86
Stockholm


Kenny Rodriguez-wallberg
Institutionen för onkologi-patologi
0858580000
kenny.rodriguez-wallberg@ki.se

Reproduktionsmedicin
Karolinska Universitetssjukhuset Huddinge
141 86
Stockholm