Course catalogue doctoral education - VT19

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Title Positron emission tomography imaging of the CNS
Course number 2362
Programme Neurovetenskap
Language English
Credits 1.5
Date 2019-03-18 -- 2019-03-22
Responsible KI department Institutionen för klinisk neurovetenskap
Specific entry requirements
Purpose of the course The course is aimed at understanding the principles of PET, the methodology used for neuroreceptor imaging and quantification, as well as to get insight in important research ongoing in the field and in the clinical applications of PET.
Intended learning outcomes On completion of the course the students will be able to explain the basic outcome measures obtained from PET studies, to describe the methodology used for neuroreceptor quantification and to generate ideas on how PET can be applied to a clinical research question or hypothesis.
Contents of the course This course will cover the basic principles of positron emission tomography, development of radioligands and CNS drugs, and quantification of neurotransmitter systems. At an applied level, the course will focus on selected imaging biomarkers to study the pathophysiology and treatment of major CNS disorders such as schizophrenia, depression, attention-deficit hyperactivity disorder and neurodegenerative disorders such as Alzheimer´s and Parkinson´s disease. Specific attention will be given to new approaches for diagnostic purposes.
Teaching and learning activities The course will include lectures in the morning and seminars or discussions with the students in the afternoon. Two "hands-on" sessions on the analysis of PET data will be also organized. Visits of the PET-lab, the autoradiography lab and the small animal microPET facility will be organised.
Compulsory elements The participation in the lectures, seminars and the group discussions and the exam is compulsory. Special reasons of absence can be discussed with the course organizers. The compensation for the absence from any part will be done in the form of a written assignment.
Examination Assessment with written exam in addition to assessment of the contribution of the student to seminars, "hands-on session", and group discussions. The written exam consists of an essay describing the application of PET in a CNS-research area. The topic will be chosen by the student. Review of the literature is allowed.
Literature and other teaching material The course literature includes book chapters on principles of positron emission tomography and PET quantification and journal articles or reviews. The students will receive the material to prepare for the various activities and the examination in advance.
Number of students 10 - 20
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information The course is held the whole week 2019-03-18 - 2019-03-22, between 09:00-16:00. The bulk of the course will be at the Psychiatry building Karolinska Hospital, Solna, R5:02. Two afternoons will be held in computer rooms at KI campus, Solna. The course is aimed for PhD students but also PostDoc's and undergraduate students are welcome if there are positions available.
Additional course leader Andrea Varrone, Anton Forsberg Morén, Katarina Varnäs
Earlier evaluation of the course Evaluation report
Course responsible Andrea Varrone
Institutionen för klinisk neurovetenskap
08-51775043
andrea.varrone@ki.se

Karolinska Hospital, Psychiatry Building
FoUU-PET, R5:02
17176
Stockholm
Contact person Anton Forsberg
Institutionen för klinisk neurovetenskap

Anton.Forsberg@ki.se


Katarina Varnäs
Institutionen för klinisk neurovetenskap

Katarina.Varnas@ki.se