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Titel Application of epidemiological methods in aging research
Kursnummer 3131
Program 1-Ingår i flera program
Språk Engelska
Antal högskolepoäng 1.5
Datum 2019-04-01 -- 2019-04-05
Kursansvarig institution Institutionen för neurobiologi, vårdvetenskap och samhälle
Särskild behörighet Knowledge equivalent to "Epidemiology I: Introduction to epidemiology", "Biostatistics I: Introduction for epidemiologists" or corresponding courses.
Kursens syfte The aim of the course is to critically review epidemiological methods with applications to aging research. An increasing share of the population in our countries lives to very advanced age. This calls for a better understanding of the ageing process, identifying possible preventive and treatment strategies to ensure that these extra years of life gained through increased longevity are spent in good health. Geriatric epidemiology approaches these challenges by studying the health and functional status of older populations throughout the entire life span.
Kursens lärandemål After completion of the course, you as a student should be able to:
(1) Discuss the pros and cons of different analytic approaches used in geriatric epidemiology, and the possible sources of bias linked to each of these approaches.
(2) Reason about the challenges in the definition, measurement and clinical assessment of chronic diseases and multimorbidity.
(3) Explain the main methods to measure physical function, as well as its contribution to the multidimensional health assessment in older people.
(4) Depict the clinical aspects as well as risk and protective factors for dementia and cognitive decline from a life course perspective.
(5) Describe the main determinants of healthy aging and longevity, with a special focus on biological and genetic markers of human aging.
Kursens innehåll This one-week course will cover the basics of geriatric epidemiology and the critical appraisal of different study designs used in the field. It will also describe the fundamental dimensions of health in older age (chronic physical and mental diseases, physical function and frailty, and cognitive function) and the challenges linked to their measurement and assessment. Last, the main determinants of aging and longevity will be introduced from the perspective of their applicability in research and clinical practice. Each theoretical session will be followed by practical sessions related to methodological challenges in each corresponding area. The practical sessions will take place in the afternoons.
Arbetsformer The course is built on brief state-of-art lectures followed by different activities where doctoral students will be asked to put into practice and critically reflect upon the acquired knowledge. The proactive participation of the student will be pursued through group discussions, in-class quizzes, critical assessment of selected studies, and on-line literature searches.
Obligatoriska moment The individual examination (summative assessment) is compulsory.
Examination To pass the course, the student has to show that the learning outcomes have been achieved. Assessments methods used are group assignments (formative assessments) along with an individual home examination (summative assessment). Students who do not obtain a passing grade in the first examination will be offered a second chance to resubmit the examination within two months of the final day of the course.
Kurslitteratur och övriga läromedel Suggested reading: (1) Fried LP. Epidemiology of aging. Epidemiol Rev. 2000;22(1):95-106. (2) Marengoni A, et al. Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev. 2011 Sep;10(4):430-9. (3) Clegg A, et al. Frailty in elderly people. Lancet. 2013 Mar 2;381(9868):752-62. (4) Solomon A, et al. Advances in the prevention of Alzheimer's disease and dementia. J Intern Med. 2014 Mar;275(3):229-50. (5) Rizzuto D, et al. Lifestyle factors related to mortality and survival: a mini-review. Gerontology. 2014;60(4):327-35.
Antal studenter 8 - 25
Urval av studenter Eligible doctoral students, with required prerequisite knowledge, prioritized according to 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date). To be considered, submit a completed application form. Give all information requested, including a description of current research and motivation for attending, and an account of previous courses taken.
Övrig information The course is arranged in collaboration between the Epidemiology and Neuroscience Programmes, see https://ki.se/en/staff/doctoral-programmes.
The course was previously given as course number 1639.
Ytterligare kursledare
Tidigare omdöme av kursen omdöme
Kursansvarig Amaia Calderon Larrañaga
Institutionen för neurobiologi, vårdvetenskap och samhälle

Kontaktpersoner Amaia Calderon Larrañaga
Institutionen för neurobiologi, vårdvetenskap och samhälle


Debora Rizzuto
Institutionen för neurobiologi, vårdvetenskap och samhälle