Course catalogue doctoral education - HT19

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Title Health risk assessment: principles and applications
Course number 3125
Programme Miljöfaktorer och hälsa
Language English
Credits 1.5
Date 2019-03-18 -- 2019-03-22
Responsible KI department Institutet för miljömedicin
Specific entry requirements
Purpose of the course The purpose of this course is to build knowledge and understanding of the scientific method to assess risks to humans of exposure to different types of chemicals.
Intended learning outcomes Upon completion of the course, the student should be able to:
-describe the basic concepts and principles of health risk assessment of chemical substances
-explain how different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data are used in risk assessment
-assess the relevance and reliability of data used in risk assessment
-derive health based guidance values such as Acceptable Daily Intake (ADI) based on the data
-reflect on the role of health risk assessment in regulatory decision making
Contents of the course Health risk assessment of chemicals is the scientific method to assess the risk to humans of exposure to different types of chemical substances, such as pharmaceuticals, environmental pollutants, chemicals in cosmetics, clothing or other everyday products and pesticide residues, food additives and other substances in food. The course starts off with introducing the concepts in risk assessment, e.g. aims of risk assessment, role of risk assessment in risk analysis (risk assessment, risk management, risk communication), different steps in risk assessment (hazard identification, hazard characterisation, exposure assessment, risk characterisation). It moves on to the different types of data from in vivo/animal, epidemiological and in vitro studies as well as exposure data that are used in risk assessment. Thereafter it is discussed how the relevance and reliability of the data is assessed, and how different types of evidence are integrated (for example from animal and epidemiological studies). The principles on how to derive health-based guidance values such as Acceptable Daily Intake (ADI) and to derive Margins of Safety values based on the data are exercised. The course then moves on to provide examples of the role of risk assessment in regulatory decision making. Case studies of different types of risk assessments exemplify how research connects to risk assessment activities. The participants will also discuss how their own research can contribute to risk assessments.
Teaching and learning activities Teaching and learning activities include lectures, exercises and group assignments.
Compulsory elements Participation in the exercises and group assignments is compulsory. Absence can be compensated with an individual task.
Examination Examination is in the form of a written assignment and/or oral presentation.
Literature and other teaching material Health risk assessment reports and guidelines from international organisations.
Number of students 8 - 30
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information The course has previously been given with no 1561.
Additional course leader
Earlier evaluation of the course Evaluation report
Course responsible Anna Beronius
Institutet för miljömedicin

anna.beronius@ki.se
Contact person Johanna Bergman
Institutet för miljömedicin

johanna.bergman@ki.se

Nobels väg 13

17177
Stockholm