Course catalogue doctoral education - VT24

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Title Exercise in the management and prevention of metabolic diseases
Course number 1790
Programme Metabolism och endokrinologi
Language English
Credits 3.0
Date 2019-06-12 -- 2019-06-18
Responsible KI department Institutionen för molekylär medicin och kirurgi
Specific entry requirements None
Purpose of the course This course will enable doctoral students to acquire the necessary knowledge to integrate clinical and basic research knowledge and understanding, competence and skills, judgement and approach in the field of exercise physiology to prevent and treat metabolic disease.
Intended learning outcomes Participants will be able:
to explain the health-related benefits of exercise from a physiological perspective,
to integrate basic knowledge of exercise with current research topics, and
to design a research proposal to evaluate the efficacy of a specific exercise program to combat metabolic disease.
Contents of the course The aim of this course is to address the role of exercise in the prevention and treatment of diseases associated with an ever-growing sedentary population. Interactive lectures will focus on the metabolic, physiological and molecular responses to exercise in health and disease. A current understanding of the underlying molecular and cellular events that govern the acute and chronic exercise response will be provided. Topics include strategies for exercise prescription in various clinical situations including diabetes, obesity, musculoskeltal disorders and aging.
Teaching and learning activities This course will be composed of interactive seminars, lectures, laboratory practicals, group work, group presentations, discussion, and reflection.
Compulsory elements Laboratory practicals and group work are compulsory. Students that are not able to attend a part of the course must do a self-study and write an essay on the topic(s) that was missed.
Examination Students will be assessed on the following:
an oral group presentation (10 min) and contribution to the discussions in connection to this, an individual written summary of the specific project researched by the group, and contribution to a course ""Abstract Book"".
Literature and other teaching material Suggested text:
""Molecular Exercise Physiology: An Introduction 1st Edition"", Henning Wackerhage,
Stromme. Routledge; 1 edition (April 27, 2014)
Egan, B. & Zierath, J. R. Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metab 17, 162-184, 2013.
Gabriel, B. M. & Zierath, J. R. The Limits of Exercise Physiology: From Performance to Health. Cell Metab 25, 1000-1011, 2017.
Bishop, D. J., Granata, C. & Eynon, N. Can we optimise the exercise training prescription to maximise improvements in mitochondria function and content? Biochim Biophys Acta 1840, 1266-1275, 2014.
FYSS 2017 http://www.fyss.se/in-english - Chapters related to metabolic diseases.

Recent related review articles and handouts will be available before each lecture.
Number of students 15 - 40
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date). Master students and postdoctoral fellows will be also be accepted if there are seats available.
More information The course will be held from 9.00-17.00 on Wednesday June 12 until Friday June 14 and continue on Monday June 17 until Tuesday June 18. The course will take place at Karolinska Institutet, Solna campus, and the GIH (Swedish School of Sport and Health Sciences). A combined schedule featuring lectures, practical work, and group activities ensures an in depth learning experience for students.
Additional course leader
Latest course evaluation Course evaluation report
Course responsible Brendan Gabriel
Institutionen för fysiologi och farmakologi

brendan.gabriel@ki.se
Contact person Ulrika Widegren
Universitetsförvaltningen

Ulrika.Widegren@ki.se


Brendan Gabriel
Institutionen för fysiologi och farmakologi

brendan.gabriel@ki.se