Course catalogue doctoral education - HT19

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Title Basic tumor histopathology
Course number 3115
Programme Tumörbiologi och onkologi (FoTO)
Language English
Credits 1.5
Date 2019-02-18 -- 2019-03-01
Responsible KI department Institutionen för mikrobiologi, tumör- och cellbiologi
Specific entry requirements
Purpose of the course The core of this course is based on microscopic sessions tutored by expert pathologists. This approach gives an opportunity to the participants to learn the morphology/histology of different human cancers and the corresponding normal tissues and to get understanding of the complex histology of human cancers.
Intended learning outcomes At the end of the course the participants should be able to:
Distinguish normal from malignant cells in tumor tissues and be acquainted with the morphology/histology of the different tumor types, differentiation stage and tumor grade.
Recognize cellular processes in the tumor tissue and its microenvironment like mitosis, cell proliferation, pleomorphism, lineage differentiation, tumor stage, necrosis, apoptosis, neural and vascular invasion, vascularisation.
Understand ethical issues and legislation concerning biobanking and practical issues on tumor handling.
Contents of the course Tumor histopathology and grading. Introduction. Endocrine tumors. Breast tumors. Prostate tumors. Gastrointestinal tumors. CNS tumors. Hematological malignancies. Sarcoma. Gynecologycal cancers. Tumor handling and biobanking.
Teaching and learning activities The first day will include an introductory lecture covering general aspects of tumor morphology/histopathology and grading (approx 6 hrs). In the following days we will review one tumor diagnosis per day organized in 45 min introduction , followed by 2 hrs interactive microscopy sessions using a multi-headed microscope and a digital screen, guided by pathologists expert in each field. Home exercises consisting on digital images of tumors together with the clinical history are given at least twice to the students for training. For distribution of files and examination we use KI Box.
Compulsory elements 100% attendance is recommended, due that each session is exclusive and cannot be compensated for later on. The student will be asked to review the issue presented in case of absence in a session.
Examination The students will get different case studies including digital images from tumors tissues and their clinical history via the KI Box account of the course. The students will then examine the cases and provide a writen description of the relevant observations leading to a correct diagnosis and answers. Images and questions have been provided by each teaching pathologist. When appropriate, anti-plagiarism tools will be used according to the guidelines from the Board of Doctoral Education at KI.
Literature and other teaching material RECOMMENDED LITERATURE: 1. Robbins Basic Pathology ("Lilla Robbins") Edited by Kumar, Cotran, Robbins 8th edition, 2007 Saunders 2. Essential Pathology ("Lilla Rubin") Edited by Rubin 3rd edition 2001 Lippincott Williams and Wilkins 3. Diagnostic Histopathology of Tumors: 2-Volume Set with CD-ROMs by Christopher D. Fletcher Elsevier Health Sciences Pub. Date: April 2007 ISBN-13: 9780443074349
Number of students 10 - 17
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information This course has previously been given as no 2166.
Additional course leader Lorand.Kis@ki.se
Earlier evaluation of the course Evaluation report
Course responsible Bertha Brodin
Institutionen för mikrobiologi, tumör- och cellbiologi
08-517 752 44
Bertha.Brodin@ki.se
Contact person Loránd Kis
Institutionen för onkologi-patologi

lorand.kis@ki.se