Course catalogue doctoral education - HT19

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Title Basic Immunology
Course number 3139
Programme Allergi, immunologi och inflammation (Aii)
Language English
Credits 3.0
Date 2019-02-04 -- 2019-04-05
Responsible KI department Institutionen för medicin, Solna
Specific entry requirements
Purpose of the course The student will learn basic concepts in immunology and meet the Immunology faculty at Karolinska Institutet. This course is a good starting point for more advanced courses in immunology.
Intended learning outcomes To understand basic principles of innate and adaptive immunity and how different components of the immune system cooperate.
To be able to relate, compare and understand experimental aspects of immune-related disease in a clinical perspective.
To adapt knowledge gained of the function of the immune system by being able to analyze and discuss an immunological/clinical case (group project).
To present the group project and discuss the results as well as work in pairs with clinical cases.
Contents of the course The course is separated into two parts. In part 1 we discuss basic immunological mechanisms within the innate and adaptive immune response. In part 2 we apply the knowledge in clinical settings such as defense against infection, autoimmune and allergic disease or transplantation. Part 1: Introduction An overview of the immune system T cells B cells Antigen­presenting cells Innate vs adaptive immune responses Methods to study immune reactions. Part 2: Immune defence against bacterial and viral infections Primary immunodeficiencies Autoimmune disease Allergy Vaccination Clinical Immunology Transplantation Tumour Immunology Questions and discussions Presentation of projects.
Teaching and learning activities The course is given full­time during a total of six days separated into two parts. The teaching is mainly in lecture/seminar form but also includes individual and/or group assignments that require studies between the two course parts. Course literature (Abbas) and cases are handed out at the course start. An immunological quiz is connected to the different chapters in the book so that the student will be able to digest the relatively big material. The course is designed so that clinically active doctors will be better able to combine it with work in the clinic (Mondays and Fridays contain no scheduled course work). The purpose of dividing the course into two parts is that the participants should have time to thoroughly study the literature from part 1 (fundamental immunological mechanisms) before teaching of the applied immunology in part 2 starts. Considering the substantial literature requirement plus the cases and project work, we estimate that an extra 32h of study is needed, which is not included in the schedule.
Compulsory elements There will be no formal examination. The students will require 95% attendance/participation in lectures and other course activities to pass the course.
Examination Web-based exam on the course content. Oral presentations of small-group project work. At this occasion special attention is given to that all students are actively participating. The clinical cases are examined by written reports.
Literature and other teaching material Abul Abbas and Andrew Lichtman: Basic Immunology. (Saunders Elsevier). The book is free and is handed out at the course start. Scientific review publications (specific state-of-the-art articles that are decided at course start)
Number of students 12 - 30
Selection of students Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
More information The course is separated into two parts. In part 1 (lectures on 4-6 Feb 19 + independent course work 7-8 Feb 19) we discuss basic immunological mechanisms within the innate and adaptive immune response. In part 2 (lectures on 1-3 Apr 19, independent course work 4-5 Apr 19) we apply the knowledge in clinical settings such as defense against infection, autoimmune and allergic disease or transplantation.
All lectures will be held at Center for Molecular Medicine (CMM) lecture hall (L8:00):
February 4 - 9:00-17:00
February 5 - 9:30-17:00
February 6 - 9:00-17:00

April 1 - 9:00-17:00
April 2 - 9:30-17:00
April 3 - 9:00-17:00

The course evaluation below refers to the same course but given previously with a different course number (3038).
Additional course leader
Earlier evaluation of the course Evaluation report
Course responsible Stephen Malin
Institutionen för medicin, Solna

stephen.malin@ki.se
Contact person Taras Kreslavskiy
Institutionen för medicin, Solna

taras.kreslavskiy@ki.se