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Titel Bioinformatics analysis of gene regulation in omics data and its applications to medical problems
Kursnummer 3027
Program Cellbiologi och genetik
Språk Engelska
Antal högskolepoäng 3.0
Noteringar Kursen uppfyller kraven för en allmänvetenskaplig kurs.
Datum 2019-03-13 -- 2019-03-27
Kursansvarig institution Institutionen för biovetenskaper och näringslära
Särskild behörighet
Kursens syfte To increase the understanding of the basic principles of bioinformatics and to gain practical skills in bioinformatics analysis of genomic sequencing data.
Kursens lärandemål After the completed course, the participants will be able to understand the principles and perform basic bioinformatics analysis of genomics sequencing data. The participants will be able to plan experimental designs and to critically evaluate the appropriateness of the different sequencing based omics methods and technologies for genome-wide gene regulation studies.
Kursens innehåll Principles of gene regulation in non-disease cases and dysregulation in diseases at individual locus level as well as on genome-wide level. Principles of sequencing based genomics technologies and corresponding bioinformatics data analysis. Concrete bioinformatics data analysis by the students of selected published projects.
Arbetsformer The course consists of preparatory work, lectures, discussion, seminars and hands-on bioinformatics analysis.
Obligatoriska moment The preparation is done in the first course week without the need to be present on-site. Week 2 consists of tasks, lectures, discussions, seminars and hands-on practicals. Both parts are compulsory. Absence has to be compensated for according to the instructions from the course leader.
Examination The students will be examined for all learning outcomes by their performance in (a) submitted replies to tasks given for course week 1, (b) discussions and quizzes during the course week 2, and (c) individual presentations at the last course day of their bioinformatics analysis results conducted during course week 2.
Kurslitteratur och övriga läromedel Recent articles and websites.
Antal studenter 15 - 20
Urval av studenter Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral project (according to written motivation), 2) date for registration as a doctoral student (priority given to earlier registration date)
Övrig information The course is given in collaboration with the RIKEN Center for Integrated Medical Sciences (RIKEN IMS, http://www.ims.riken.jp/english/). The course faculty consists of invited speakers from the RIKEN IMS and from Karolinska Institutet. Please note that second week of the course, March 20 to 27, 2018, will be given at RIKEN in Yokohama, Japan. The course organizers do not provide any financial support for the trip to or accommodation in Japan. The organizers can help with finding accommodation in Japan close to RIKEN. There is a limited number of travel grants available for the course (10000 Swedish crowns including INDI). If you wish to apply for such a grant support for this course, include a motivation for this in your course application. Grant applications will be judged on the basis of the motivation in case there are more applications than available grants.
Ytterligare kursledare The course director is Dr. Carsten Daub from Karolinska Institutet and the co-director is Dr. Piero Carninci from RIKEN IMS.
Senaste kursvärdering Kursvärderingsrapport
Kursansvarig Carsten Daub
Institutionen för biovetenskaper och näringslära

Carsten.Daub@ki.se
Kontaktpersoner Matti Nikkola
Institutionen för cell- och molekylärbiologi

Matti.Nikkola@ki.se