Kurskatalog forskarutbildning - VT19

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Titel Pulmonary inflammation
Kursnummer 3145
Program Allergi, immunologi och inflammation (Aii)
Språk Engelska
Antal högskolepoäng 1.5
Datum 2019-04-08 -- 2019-04-12
Kursansvarig institution Institutet för miljömedicin
Särskild behörighet Basic immunology knowledge is required.
Kursens syfte The aim of the course is to get basic knowledge of important pulmonary diseases in terms of clinic and research. To develop this knowledge, the student should be able to formulate the questions that the student need for understanding the disease and the questions that is needed to be answered by future research. Optimally, the student should be able to create designs for experimental protocols that answer important questions.
Kursens lärandemål After the course the student should be able to show an understanding of the most important principles of lung physiology and mechanisms behind the respiratory impairment in asthma, chronic obstructive pulmonary disease (COPD), interstitial lung diseases and animal models used in respiratory research. The student should also be able to discuss the methods used for the diagnostics of the different lung diseases. Furthermore, the student should be acquainted with the research front-line in each of the lung diseases and the different models used in the research as well as be able to understand and evaluate scientific papers regarding lung diseases.
Kursens innehåll The principles and challenges of important inflammatory diseases of the lungs from a translational perspective, that is from clinical practice to experimental research. The course will be interactive between both the participants and the lecturers. The course is focused on the following topics: asthma, chronic obstructive pulmonary disease (COPD), interstitial lung diseases and animal modesl used in respiratory research. Lectures cover epidemiology, symptoms and differential diagnosis, diagnostic methods, pathogenic mechanisms, treatment (existing, future). Demonstrations cover methods that are used for diagnostic and/or research purposes: e.g. inhalation provocation, allergy diagnosis, spirometry, peak expiratory flow (PEF) measurements, chest Xray, computer tomography, other imaging methods, bronchoscopy/broncholaveolar lavage, flow cytometry etc. For all the diseases specific lectures will cover how the research in each field has evolved, were the front-line is today.
Arbetsformer The course, given during one week, comprises five days of scheduled studies that include review, group case work and preparation for the web-based examination. The general format is as follows: Each day starts with a case presentation and discussion in groups, when the group consisting of students with different backgrounds have a short brainstorming how to solve the case with regard to cause of disease, diagnostics, treatments and research. This is followed by lectures before lunch. After lunch there will be demonstrations and further lectures, and the day concludes with group discussions about the cases. In addition, each group is assigned one case that they will study more in depth in a group to discuss before they present it to the whole class for open discussion on the last day. The case work may include studying aspects of the disease not covered by the lectures/demonstrations, suggesting novel treatments and how they could be evaluated, identify areas where more research into mechanisms is needed and propose hypotheses and how these can be tested in a patient or animal model setting.
Obligatoriska moment All parts are compulsory. In case of absence, a written report that covers the part that was will be requested.
Examination Web-based written examination. Oral presentations of small-group project work. At this occasion special attention is given to that all students are actively contributing.
Kurslitteratur och övriga läromedel Selected and up-to-date scientific review papers will be handed out during the course.
Antal studenter 8 - 20
Urval av studenter The course will be held 9.00-17.00 from Monday to Friday. The first three and a half days consist of lectures and group discussions. During the last days group work together with presentations will take place. The course will end with a web examination.
Övrig information
Ytterligare kursledare Kursansvarig: Mikael Adner, Associate Professor, IMM, mikael.adner@ki.se Amanuens: Susanna Kumlien Georén, Senior Lab Manager, PhD, CLINTEC, susanna.georen@ki.se
Tidigare omdöme av kursen Not available
Kursansvarig Mikael Adner
Institutet för miljömedicin

mikael.adner@ki.se
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